Results 71 to 80 of about 156,025 (281)

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

open access: yesAdvanced Intelligent Systems, EarlyView.
FTGRN introduces an LLM‐enhanced framework for gene regulatory network inference through a two‐stage workflow. It combines a Transformer‐based model, pretrained on GPT‐4 derived gene embeddings and regulatory knowledge, with a fine‐tuning stage utilizing single‐cell RNA‐seq data.
Guangzheng Weng   +7 more
wiley   +1 more source

The Relationship between Renal Resistive Index and Complexity of Coronary Lesions in Patients with Stable Coronary Artery Diseases

open access: yesReviews in Cardiovascular Medicine
Background: The most common cause of coronary artery diseases (CAD) is atherosclerosis. The synergy between percutaneous coronary intervention with TAXUS™ and cardiac surgery (SYNTAX) score was used to assess complex CAD lesions.
Hesham Refaat, Ayman Tantawy
doaj   +1 more source

A detailed analysis of phrase-based and syntax-based machine translation: the search for systematic differences [PDF]

open access: yes, 2012
This paper describes a range of automatic and manual comparisons of phrase-based and syntax-based statistical machine translation methods applied to English-German and English-French translation of user-generated content.
Jennifer Foster   +4 more
core   +1 more source

How Important is Syntactic Parsing Accuracy? An Empirical Evaluation on Rule-Based Sentiment Analysis

open access: yes, 2017
Syntactic parsing, the process of obtaining the internal structure of sentences in natural languages, is a crucial task for artificial intelligence applications that need to extract meaning from natural language text or speech.
Alonso-Alonso, Iago   +2 more
core   +1 more source

SYNTAX Score in Patients with High Computed Tomography Coronary Calcium Score

open access: yesJournal of Clinical Imaging Science, 2016
Objectives: To study the conventional coronary angiogram ( CA) findings in patients with high coronary calcium on multidetector computed tomogram. Materials and Methods: Fifty patients with coronary calcium high enough in its extent and location to interfere with the interpretation of a contrast-filled coronary artery for a significant lesion were ...
Hegde, Madhav, Rajendran, Ravindran
openaire   +2 more sources

AI Guided Protein Design for Next‐Generation Autogenic Engineered Living Materials

open access: yesAdvanced Intelligent Systems, EarlyView.
Autogenic engineered living materials (ELMs) integrate biology and materials science to create self‐regenerating and self‐healing materials. This perspective highlights emerging strategies in protein engineering and AI‐guided de novo design to expand the capabilities of autogenic ELMs.
Hoda M. Hammad, Anna M. Duraj‐Thatte
wiley   +1 more source

ПРОГНОСТИЧЕСКАЯ ЗНАЧИМОСТЬ ШКАЛ SYNTAX SCORE И SYNTAX SCORE II В ОТНОШЕНИИ РЕЗУЛЬТАТОВ ВЫПОЛНЕНИЯ ЧКВ У ПАЦИЕНТОВ С ТЯЖЕЛЫМИ ФОРМАМИ КОРОНАРНОГО АТЕРОСКЛЕРОЗА В ТЕЧЕНИЕ ТРЕХ ЛЕТ НАБЛЮДЕНИЯ

open access: yesЕвразийский Кардиологический Журнал, 2019
Классическая анатомическая шкала SYNTAX Score является одной из наиболее распространенных и обладающих обширной доказательной базой. Тем не менее, коморбидный фон пациентов значительно различается, что послужило основанием для разработки и внедрения ...

doaj  

Prognostic Value of Quantitative Flow Ratio Combined with SYNTAX Scores I/II in Multivessel Coronary Artery Disease: A Small-Sample, Single-Center Study

open access: yesReviews in Cardiovascular Medicine
Background: A fractional flow reserve (FFR)-fixed-SYNTAX score could decrease the number of high-risk patients. This study explored the prognostic value of non-invasive quantitative flow ratio (QFR)-fixed-SYNTAX I/II scores in ...
Shuyi Zhang   +9 more
doaj   +1 more source

Bayesian Optimisation for the Experimental Sciences: A Practical Guide to Data‐Efficient Optimisation of Laboratory Workflows

open access: yesAdvanced Intelligent Systems, EarlyView.
This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He   +2 more
wiley   +1 more source

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