Results 61 to 70 of about 9,993 (246)

Linking Diet and Homocysteine to complexity of coronary artery disease using SYNTAX score – A cross sectional study

Clinical Epidemiology and Global Health
Background: Hyperhomocystinemia (HHcy) attributed to various causes is considered an independent risk factor in the development and progression of coronary artery disease (CAD).
Sowndarya Kollampare, Anupama Hegde, Arpit Jain, Padmanabh Kamath, Ramya Shenoy, Poornima A. Manjrekar   +5 more
doaj   +1 more source

Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting

Chronic Diseases and Translational Medicine, 2020
Objective: To identify risk factors of saphenous vein graft (SVG) failure and to investigate the utility of anatomical SYNTAX score (SS) and SYNTAX score II (SS-II) in predicting SVG failure. Methods: A total of 598 patients who underwent angiography for
Jia-Hui Li, Xian-Tao Song, Xue-Yao Yang, Wen-Yi Zhang, Hao-Ran Xing   +4 more
doaj   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

ПРОГНОСТИЧЕСКАЯ ЗНАЧИМОСТЬ ШКАЛ SYNTAX SCORE И SYNTAX SCORE II В ОТНОШЕНИИ РЕЗУЛЬТАТОВ ВЫПОЛНЕНИЯ ЧКВ У ПАЦИЕНТОВ С ТЯЖЕЛЫМИ ФОРМАМИ КОРОНАРНОГО АТЕРОСКЛЕРОЗА В ТЕЧЕНИЕ ТРЕХ ЛЕТ НАБЛЮДЕНИЯ

Евразийский Кардиологический Журнал, 2019
Классическая анатомическая шкала SYNTAX Score является одной из наиболее распространенных и обладающих обширной доказательной базой. Тем не менее, коморбидный фон пациентов значительно различается, что послужило основанием для разработки и внедрения ...

doaj  

Does CHA2DS2-VASc Score Predict MACE in Patients Undergoing Isolated Coronary Artery Bypass Grafting Surgery?

Brazilian Journal of Cardiovascular Surgery, 2019
Objective: To evaluate the prognostic value of CHA2DS2-VASc score in individuals undergoing isolated coronary artery bypass grafting (CABG) surgery. Methods: Records of consecutive 464 patients who underwent elective isolated CABG, between January 2015 ...
Muhsin Kalyoncuoglu, Semi Ozturk, Mazlum Sahin   +2 more
doaj   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Pattern of coronary artery disease and its correlation with risk factors and severity of disease in patients with established peripheral artery disease: Doppler and angiographic study

Heart Vessels and Transplantation
Objective: Peripheral arterial disease (PAD) is one of the underdiagnosed and undertreated vascular disease burden irrespective of symptoms in India.
Riyaz Charaniya, Ajinkya Borhade, Tarunkumar Madan, Dinesh Joshi, Krutika Patel, Anand Dhakne, Himani Upadhyaya, Parth Thakkar   +7 more
doaj   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

Advanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang, Chenhui Li, Dongjiao Wang, Qibin Wu, Zhen Zeng, Huiming Guo, Han Cheng, Songbi Chen, Hongxing Cao, Hongmei Cheng, Jianghui Xie, Youxiong Que   +11 more
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source