Results 51 to 60 of about 332,938 (279)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Molecules, 2018 The separation of phenolic compounds by supercritical fluid extraction has been widely studied throughout the last two decades. This is evidenced by a number of publications and articles. Supercritical fluid extraction (SFE) has become thus the effective
Katarzyna Tyśkiewicz +2 more
doaj +1 more source
Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals [PDF]
, 2018 Chemical manufacturing is often done at large facilities that require a sizable capital investment and then produce key compounds for a finite period. We present an approach to the manufacturing of fine chemicals and pharmaceuticals in a self-contained ...
Cronin, Leroy +6 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Síntese do anti-helmíntico praziquantel,a partir da glicina
Química Nova, 1999 This paper deals mainly with the synthesis of praziquantel, a powerful anti-helminthic used against schistosomiasis, an endemic disease which infest millions of people around the world.
Novaes Maria Rita Carvalho Garbi +2 more
doaj
DFT Study on the Mechanism of Iron-Catalyzed Diazocarbonylation
Molecules, 2020 The mechanism of the carbonylation of diazomethane in the presence of iron–carbonyl–phosphine catalysts has been investigated by means of DFT calculations at the M06/def-TZVP//B97D3/def2-TZVP level of theory, in combination with the SMD solvation method.
Tímea R. Kégl +2 more
doaj +1 more source
Microbiology Spectrum, 2022 Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target.
Sandra Hoefgen +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Applied Sciences, 2022 This study investigated the impact of subcritical water extraction parameters on the polyphenols and flavonoids content in extracts made of the bark of walnut (Juglans regia L.), as well as antioxidant activity measured using the DPPH and FRAP methods ...
Piotr Kamiński +4 more
doaj +1 more source
A review of plasma liquid interactions for nanomaterial synthesis
, 2015 In this review, we have summarized the recent advances and present conditions of the nanomaterials synthesis from the plasma-liquid interactions. A theoretical analysis for the nanomaterials synthesis process is presented by analyzing the experimental ...
Chen, Qiang, Li, Junshuai, Li, Yongfeng
core +1 more source