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Synthetic organelles

Emerging Topics in Life Sciences, 2019
One approach towards the creation of bottom-up synthetic biological systems of higher complexity relies on the subcompartmentalization of synthetic cell structures using artificially generated organelles — roughly mimicking the architecture of eukaryotic cells.
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Synthetic evolution

Nature Biotechnology, 2019
The combination of modern biotechnologies such as DNA synthesis, λ red recombineering, CRISPR-based editing and next-generation high-throughput sequencing increasingly enables precise manipulation of genes and genomes. Beyond rational design, these technologies also enable the targeted, and potentially continuous, introduction of multiple mutations ...
Anna J. Simon   +2 more
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Synthetic microvessels

Journal of Thrombosis and Haemostasis, 2013
The microvasculature is an immense organ that defines the environmental conditions within tissues in both health and disease, and is vital for the proper functions of all tissues. Here, we describe existing tools to study vascular cell function and our work using one platform of in vitro microvessels, which we employed to study vessel structure and ...
J A, López, Y, Zheng
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Synthetic wisdom

Annals of the New York Academy of Sciences, 2016
Wisdom is a special kind of virtue. It is not to be identified with any outstanding cognitive ability—like having a prodigious memory or knowing a lot. Rather it consists in seeing what is most important and most valuable, either within a particular domain or in life as a whole. In the life of a wise person, that insight should be accompanied by traits
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Synthetic multicellularity

Trends in Cell Biology, 2012
The ability to synthesize biological constructs on the scale of the organisms we observe unaided is probably one of the more outlandish, yet recurring, dreams humans have had since they began to modify genes. This review brings together recent developments in synthetic biology, cell and developmental biology, computation, and technological development ...
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Synthetic surfactants

Seminars in Fetal and Neonatal Medicine, 2023
Fernando, Moya   +3 more
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Synthetic Tetrahydrocannabinol

Journal of Forensic Sciences, 1983
Abstract This paper presents the synthetic route used and the identification of the precursors and reaction products in a clandestine laboratory manufacture of cannabidiol (CBD), μ9-cis-tetrahydrocannabinol (μ9)-cis-THC), and μ9-trans-tetrahydrocannabinol (μ9-trans-THC).
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Engineering living therapeutics with synthetic biology

Nature Reviews Drug Discovery, 2021
Andres Cubillos-Ruiz   +2 more
exaly  

Synthetic Penicillin

Science, 1946
V, du Vigneaud   +4 more
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Synthetic polymers.

Seminars in interventional cardiology : SIIC, 1998
For several decades, synthetic polymers have been the subject of study for vascular applications. Several materials have been tested to date, both for coating and replacing metal stents. While conflicting data between some of these studies exist, these may in part be related to characteristics secondary to the synthetic polymer itself: surface ...
van Beusekom, H. M.   +2 more
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