Results 31 to 40 of about 93,895 (266)

Vibration Studies on Fiber Reinforced Composites – a Review

open access: yesJournal of Natural Fibers, 2023
Fiber reinforced composites materials have been much more attention in the materials system by the researchers since their unique performance in various structural applications.
Gananiar Kalusuraman   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanical and Acoustic Performance of Plantain (Musa Paradisiacal) Fibre Reinforced Epoxy Bio-Composite

open access: yesJournal of Natural Fibers, 2022
Natural fiber-reinforced polymer biocomposites are very attractive materials utilized for many applications owing to their high mechanical and acoustic properties.
Patrick Ehi Imoisili, Tien-Chien Jen
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Fibrous extracellular matrix (ECM) proteins provide mechanical structure and adhesive scaffolding to resident cells within stromal tissues. Aligned ECM fibers play an important role in directing morphogenetic processes, supporting mechanical loads, and ...
Harrison L. Hiraki   +11 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Treatment of traumatic crush injury using a synthetic hybrid-scale fiber matrix in conjunction with split-thickness skin graft

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases, 2022
Crush injuries to the forefoot can result in prolonged treatment and disability and may necessitate amputation. Providing prompt and definitive treatment, including early debridement and wound coverage, is important for enabling favorable clinical ...
Curt J. Martini   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Experimental and Numerical Investigation on the Effect of Different Types of Synthetic Fibers on the Flexure Behavior and Mechanical Properties of 3D Cementitious Composite Printing Provided with Cement CEM II/A-P

open access: yesBuildings
Concrete printing in three dimensions is believed to be an innovative construction method. Numerous researchers conducted laboratory experiments over the past decade to examine the behavior of concrete mixtures and the material properties that are ...
Ahmed M. Yassin   +2 more
doaj   +1 more source

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