Results 21 to 30 of about 352,654 (215)

Synthetic media, political disinformation, and the erosion of public trust: a systematic review and synthetic epistemic destabilization model

Frontiers in Political Science
IntroductionAI-generated synthetic media pose structural challenges to democratic communication and institutional trust.MethodsSystematic review of 74 empirical studies (2018–2025) following SWiM guidelines, with vote-counting across four outcome domains.
Mohanad Alamin, Saleh Abied Alrached, Mathani Hassan Abasher, Khalid Mahmoud, Abdulla Altaher, Elsir Ali Saad Mohamed   +5 more
doaj   +1 more source

Sociotechnical Change: Tracing Flows, Languages, and Stakes Across Diverse Cases| “A Fountain Pen Come to Life”: The Anxieties of the Autopen

International Journal of Communication, 2023
The autopen is a technology widely used by celebrities and politicians—often covertly—to automatically sign letters and other media. When the autopen’s use comes to light, public indignation often follows; learning that something has been signed ...
Pegah Moradi, Karen Levy
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Seeking to define deepfakes from U.S. state laws

Communication & Society (Formerly Comunicación y Sociedad)
In six years, the word deepfake has gone from a niche on Reddit to the main object of research for hundreds of researchers and to the front line of concern of many policymakers.
João-Paulo Meneses
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

DeepFakeX: A Comprehensive Multimodal Deepfake Dataset for Research and Analysis

Data
The expanding capabilities of deep learning-based media synthesis have intensified concerns regarding the authenticity of digital content and the reliability of forensic analysis tools.
Sonia Salman, Jawwad Ahmed Shamsi, Rizwan Qureshi   +2 more
doaj   +1 more source

Replicating carbonaceous vug in synthetic porous media

MethodsX, 2018
This paper presents an alternative method of creating vuggy glass-bead core proxies, which can be used to investigate the effects of pore-scale features on carbonate petrophysical properties.
Hasan J. Khan, David DiCarlo, Maša Prodanović   +2 more
doaj   +1 more source