Results 41 to 50 of about 141,422 (269)

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

Prevention of congenital syphilis: The current state of legislation and public health guidelines

Pregnancy
Syphilis infection among pregnant people and congenital syphilis rates have risen considerably in the United States, leading to adverse maternal and neonatal health outcomes.
Rose Darcy, Laurie Ayala, Maura Quinlan, Danucha Brikshavana, Anne Statton, Irina Tabidze, Helen Cejtin, Jennifer Jao, Sarah Sutton, Nigel Madden, Mariana Espinal, Lynn M. Yee   +11 more
doaj   +1 more source

The impact of syphilis screening among female sex workers in China: a modelling study. [PDF]

PLoS ONE, 2013
BackgroundIn China, female sex workers (FSWs) are at high risk of syphilis infection, but are hard to reach for interventions. Point-of-care testing introduces opportunities for expanding syphilis control measures.
Kate M Mitchell, Andrew P Cox, David Mabey, Joseph D Tucker, Rosanna W Peeling, Peter Vickerman   +5 more
doaj   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Evaluating the MedMira Multiplo® Complete Syphilis (TP/nTP) antibody test in a sexually transmitted infection clinic in Ottawa, Canada: increased rapid diagnosis and improved antibiotic stewardship

BMC Infectious Diseases
Background Syphilis now affects every population and serology is the mainstay of diagnosis. The issue is that serology has a turnaround time of several days. One solution is point-of-care tests (POCTs), which can provide results in minutes.
Patrick O’Byrne, Riley Dillabough, Kathleen Whyte, Lauren Orser, Vanessa Tran, Venkata R. Duvvuri, Raymond Tsang   +6 more
doaj   +1 more source

MONITORING OF SYPHILIS IN BLOOD DONATIONS: CORRELATIONS WITH NOTIFIED CASES IN BRAZIL

Hematology, Transfusion and Cell Therapy
Background: Syphilis is a public health problem with traditional surveillance limited to clinical monitoring data; asymptomatic and low-risk populations rarely undergo diagnostic testing.
NA Braga, S Mateos, V Avelino-Silva, D Warden, M Ribeiro, L Amorim, P Loureiro, N Fraiji, EC Sabino, B Custer   +9 more
doaj   +1 more source

Estimating Benzathine Penicillin Need for the Treatment of Pregnant Women Diagnosed with Syphilis during Antenatal Care in High-Morbidity Countries.

PLoS ONE, 2016
BackgroundCongenital syphilis continues to be a preventable cause of global stillbirth and neonatal morbidity and mortality. Shortages of injectable penicillin, the only recommended treatment for pregnant women and infants with syphilis, have been ...
Melanie M Taylor, Stephen Nurse-Findlay, Xiulei Zhang, Lisa Hedman, Mary L Kamb, Nathalie Broutet, James Kiarie   +6 more
doaj   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

The prevalence of vertical transmission of human immunodeficiency virus and associated factors among exposed infants in Eastern Lake zone and Southern Highland of Tanzania: a cross-sectional study

HIV Research & Clinical Practice
Background Globally, the rate of antiretroviral therapy coverage for pregnant women living with human immunodeficiency virus (HIV) increased by 38% between 2010 and 2015 but only by 2% between 2016 and 2020.
Peter Richard Torokaa, Loveness Urio, Ambwene Mwakalobo, Godfrey Eriyo, Alex Sifael Magesa, Regnald Julius, Alice Kyalo, James N. Allan, David J. Osima, Focus M. Shao, Joseph Mziray, Leah Mtui, Theopista P. Mbago, Masanja Robert, Mukome A. Nyamhagatta, Michael Msangi, Maro Chacha, Hasra Charles, Grace Denis Mtui, Mtebe Majigo, Agricola Joachim   +20 more
doaj   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source