Results 131 to 140 of about 2,603,336 (302)

Air Force space power technology program [PDF]

open access: yes
The military spacecraft power subsystem design requirements, developments goals, and planned technology efforts are summarized. The mission drivers of performance (weight and volume), hardening (survivability), autonomy, reliability, and miniaturization ...
Barthelemy, R.   +2 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Automatic specification of reliability models for fault-tolerant computers [PDF]

open access: yes
The calculation of reliability measures using Markov models is required for life-critical processor-memory-switch structures that have standby redundancy or that are subject to transient or intermittent faults or repair.
Liceaga, Carlos A., Siewiorek, Daniel P.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

ASSIST: User's manual [PDF]

open access: yes
Semi-Markov models can be used to compute the reliability of virtually any fault-tolerant system. However, the process of delineating all of the states and transitions in a model of a complex system can be devastingly tedious and error-prone.
Johnson, S. C.
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Reliability Assessment and Reliability Prediction of CubeSats through System Level Testing and Reliability Growth Modelling [PDF]

open access: yes, 2018
This dissertation describes a set of methods used to track, assess and predict the reliability of CubeSats through system level testing and reliability growth modelling. In the last decade, CubeSats have matured from educational tools into accepted scientific and commercial assets, with more than 700 of those standardized satellites launched so far.
openaire  

Characteristics and performance of the ESTEC large space simulator cryogenic system [PDF]

open access: yes
The final concept and performance characteristics of the Large Space Simulator (LSS) at ESTEC, The Netherlands are discussed. The LSS cryogenics system has proven its operational capabilities under simulated heat load conditions and provides sufficient ...
Amlinger, H., Bosma, S. J.
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Reliability analysis of subsea control system using FMEA and FFTA

open access: yesScientific Reports
Reliability technology plays a significant role in ensuring the safe operation of the subsea control system. To perform a comprehensive analysis of the reliability of complex systems, a combination of Failure Mode and Effects Analysis (FMEA) and Fuzzy ...
Chao Liu   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy