Results 41 to 50 of about 2,603,336 (302)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Research on Reliability Modeling, Allocation and Prediction of Chemical Production System

open access: yesMATEC Web of Conferences, 2018
Reliability allocation and prediction play an important role in the chemical production system, controlling the significance of each production allocation and predicting system reliability to analyze the designs in each system or integrated system if ...
Miao Yongchun   +2 more
doaj   +1 more source

Classes of Byzantine Fault-Tolerant Algorithms for Dependable Distributed Systems. [PDF]

open access: yes, 1998
This thesis concentrates on the design of new algorithms for fault-tolerant systems based on system-level hardware masking redundancy. It is argued that any system in which a reliability improvement of at least a factor 100 is required should be based on
Postma, André
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

A System-Level Reliability Growth Model for Efficient Inspection Planning of Offshore Wind Farms

open access: yesJournal of Marine Science and Engineering
Fatigue damage can lead to failures of structural systems. To reduce the failure risk and enhance the reliability of structural systems, inspection and maintenance interventions are required, and it is important to develop an efficient inspection ...
Linsheng Li, Guang Zou
doaj   +1 more source

Optimization of system reliability for multi-level RAPs in intuitionistic fuzzy atmosphere using genetic algorithm

open access: yesResults in Control and Optimization, 2022
Modular redundancy plays a significant role for designing a reliable system. This study examines the optimization of system reliability in a modular redundancy allocation problem in crisp and intuitionistic fuzzy atmospheres with the goal of maximizing ...
Rajesh Paramanik   +4 more
doaj   +1 more source

On the Shannon Cipher System With a Wiretapper Guessing Subject to Distortion and Reliability Requirements

open access: yes, 2002
In this paper we discuss the processes in the Shannon cipher system with discrete memoryless source and a guessing wiretapper. The wiretapper observes a cryptogram of $N$-vector of ciphered messages in the public channel and tries to guess successively ...
Haroutunian, Evgueni
core   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Methodology for Estimatiom of Logistics Risks and Reliability in Cargo Delivery

open access: yesНаука и техника, 2005
Reliability in delivery and risks arising in the process of cargo delivery can be estimated with the help of the presented index system. The offered methods for assigning a level of planned reliability in delivery and level of reliability in delivery of ...
O. G. Drozdovskaya
doaj   +1 more source

Reliability Analysis of the MSC System [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2003
MSC (Multi-Spectral Camera) is the payload of KOMPSAT-2, which is being developed for earth imaging in optical and near-infrared region. The design of the MSC is completed and its reliability has been assessed from part level to the MSC system level. The
Young-Soo Kim   +3 more
doaj   +1 more source

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