Results 161 to 170 of about 42,834,864 (267)

Relative importance of climate versus socio-environmental development changes to 2050 in rural coastal Bangladesh-a system analysis. [PDF]

Reg Environ Change
Lázár AN, Nicholls RJ, Hutton CW, Payo A, Adams H, Haque A, Clarke D, Salehin M, Hunt A, Allan A, Adger WN, Rahman MM, Smith R.   +12 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Cost-effectiveness of three-level cervical disc arthroplasty <i>vs.</i> anterior discectomy and fusion: a comparative single-system analysis. [PDF]

J Spine Surg
Hoglund ZT, Kathawate VG, Sollenberger CS, Wu AQ, Englander R, Rani N, Saadoun J, Massaad E, Schuster JM, Marcotte PJ, Shammassian BH, Welch WC, Casper DS, Ozturk AK, Ali ZS, Malhotra NR, Shin JH, Judy BF.   +17 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Drug-drug interactions between sex hormones and analgesics linked to thromboembolic events: an FDA adverse event reporting system analysis. [PDF]

Front Pharmacol
Yamazaki S, Onda K, Masuyama K.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Ex-ante assessment of novel technologies for bio-based chemicals production [PDF]

, 2018
Moncada Botero, J., Energy System Analysis   +1 more
core  

Telehealth as a Strategy to Expand Access in Brazil's Unified Health System: Analysis of São Paulo State's Experience Across the Three Levels of Health Care. [PDF]

JMIR Form Res
Buto MSS, Carvalho GB, Garcia ML, de Andrade MCCLB, de Lima RR, Cerri GG, Carvalho CRR.   +6 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Combining response surface methodology and measurement system analysis to identify melt flow index of hygrothermal-sensitive composites. [PDF]

Sci Rep
Su N, Liu X, Chen X, Gu J, Bai J.
europepmc   +1 more source