Results 91 to 100 of about 19,670,712 (302)

Adaptive Governance and sub-national Climate Change Policy: A comparative analysis of Khyber Pukhtunkhawa and Punjab Provinces in Pakistan

open access: yes, 2019
This study explores the adaptive governance and effective implementation of climate policies at the subnational level in a developing country context. We focused on Pakistan as our central case as it is considered one of the most vulnerable countries to ...
H. Ali, Saleem, Mumtaz, Muhammad
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Complexity in Plasma - A Grand View of Self- Organization

open access: yes, 1994
"The central theme of the Complexity is the inquest of the creation of ordered structure in nature. Extensive computer simulations on plasmas have revealed that self-organization is governed by the three key processes, i.e.
"Sato, T.   +1 more
core  

Complexity, economics, and innovation policy: How two kinds of science lead to two kinds of economics and two kinds of policy

open access: yes, 2017
One interpretation of complexity science is that it distinguishes two types of science—an equilibrium science of forces, as begun by Newton, and a complexity science of rules, as exemplified by Wolfram (2002).
Potts, Jason, Jason Potts
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Responsive Governance and Harmful Microbial Blooms on Lake Erie: An ABM Approach

open access: yes, 2019
In general, decision makers tend to respond to problems rather than prevent them. In political science, this process of responsive governance is associated with complex dynamics such as availability cascades and punctuated equilibrium.
Pavlovich, Tyler, Webster, DG
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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