Results 71 to 80 of about 4,812,564 (245)
Review and Prospect of Urban Waterlogging Decision Support System
With advantages of reasonable, rapid and accurate aid decision making, the urban waterlogging decision support system can comprehensively improve the ability of flood and waterlogging control.
LU Jiantao +4 more
doaj
Development of a Large, Low-Cost, Instant 3D Scanner
Three-dimensional scanning serves a large variety of uses. It can be utilized to generate objects for, after possible modification, 3D printing. It can facilitate reverse engineering, replication of artifacts to allow interaction without risking cultural
Jeremy Straub, Scott Kerlin
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Development of Telemedicine System [PDF]
The tendency of computer technologies implementation to all areas of life is obvious and indisputable. Informatization of such area as medicine, gives huge advantage to health care service. For example, use of telemedicine technologies will allow making professional medical care to the removed patient.
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Order component extraction technology for predictive maintenance system in rotary machine
The most obvious difference between the recent smart factory and the traditional automation factory is that the techniques about Predictive Maintenance (PdM) are introduced, PdM is also one of the key enabling technologies in Industry 4.0.
Lu Yan +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Developing cyber-resilient systems :
NIST Special Publication (SP) 800-160, Volume 2, Revision 1, focuses on cyber resiliency engineering an emerging specialty systems engineering discipline applied in conjunction with systems security engineering and resilience engineering to develop survivable, trustworthy secure systems.
Ron Ross +4 more
openaire +1 more source

