Results 241 to 250 of about 32,200,596 (338)

A System dynamics analysis of the factors influencing the promotion of prefabricated decoration, based on a co-occurrence network. [PDF]

PLoS One
Wang Y, Liu J, Zhang G, Geng X, Liu Y.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Engaging Hospital Staff to Identify Levers for Adoption of Clinical Decision Support: Protocol for a Single-Site Case Study Using System Dynamics Group Model Building.

JMIR Res Protoc
Sperber NR, Zimmerman LE, Caton L, Rust T, Bedoya A, Haas S, Orlando L, Goldstein B.   +7 more
europepmc   +1 more source

A disaggregated system dynamics and agent-based modeling of the water-energy-food nexus for optimizing water allocation. [PDF]

Sci Rep
Zarei S, Bozorg-Haddad O, Nikoo MR, Loáiciga HA.   +3 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Applying a system dynamics approach for decision-making in software testing projects. [PDF]

PLoS One
Li W, Fang CC.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Advancing Applications of System Dynamics in Critical Food Systems Research Comment on "Using System Dynamics to Understand Transnational Corporate Power in Diet-Related Non-communicable Disease Prevention Policy-Making: A Case Study of South Africa". [PDF]

Int J Health Policy Manag
Brown AD, Sherriff S, Wood B, Allender S, Mitchell F, Paradies Y, Browne J.   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Understanding energy system dynamics in a changing climate: Insights for first responders and risk managers. [PDF]

iScience
Mille J, Charlton D, de Ruiter MC, Stevens R, Haklay M, Edwards SJ.   +5 more
europepmc   +1 more source