Results 51 to 60 of about 1,185,764 (268)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Precise and Continuous Biomass Measurement for Plant Growth Using a Low-Cost Sensor Setup
SensorsContinuous and accurate biomass measurement is a critical enabler for control, decision making, and optimization in modern plant production systems. It supports the development of plant growth models for advanced control strategies like model predictive ...
Lukas Munser +5 more
doaj +1 more source
A Self-Powered, Threshold-Based Wireless Sensor for the Detection of Floor Vibrations
Sensors, 2018 Smart buildings will soon be a reality due to innovative Internet of Things (IoT) applications. IoT applications can be employed not only for energy management in a building, but also for solving emerging social issues, such as inter-floor noise-related ...
Byung C. Jung +2 more
doaj +1 more source
European Physical Journal C: Particles and Fields, 2020 A connection between the deformed Duffin–Kemmer–Petiau (DKP) algebra and an extended system of the parafermion trilinear commutation relations for the creation and annihilation operators $$a^{\pm }_{k}$$ a k ± and for an additional operator $$a_{0}$$ a 0
Yu. A. Markov, M. A. Markova
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Optimisation of real-time control for hybrid diesel–PV–battery systems
International Journal of Sustainable Energy, 2017 Hybrid diesel–PV–battery systems are one of the most cost effective options for off-grid power generation. A methodology for the optimal operation of such systems for an off-grid application is proposed in this paper.
Julia Sachs, Kevin Tom, Oliver Sawodny
doaj +1 more source
Simulation of Adhesive Contact of Soft Microfibrils
Lubricants, 2020 Adhesive contact between a flat brush structure with deformable microfibrils and an elastic half space is numerically simulated. The stiffness of pillars is modeled by linear springs.
Xin He, Qiang Li, Valentin L. Popov
doaj +1 more source