Results 141 to 150 of about 18,605,759 (251)

Feature Selection with the Boruta Package [PDF]

This article describes a R package Boruta, implementing a novel feature selection algorithm for finding \emph{all relevant variables}. The algorithm is designed as a wrapper around a Random Forest classification algorithm.
Witold R. Rudnicki, Miron B. Kursa
core  

Load identification method for pepper harvesting drum based on dynamic chaotic characteristics of vibration-torque coupling. [PDF]

PLoS One
Wei C, Lei J, Qin X, Xiao Y, Wang Z, Wang S, Li B, Guo X, Wang C.   +8 more
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Envelope addressed to U.S. Feature Service

, 1922
: Envelope addressed by Dr. Carlos Montezuma to the U.S. Feature Service, New York, NY. Envelope is thought to have held volume 8, issue #19 of the Wassaja Newsletter.Newsletter available at https://repository.asu.edu/items ...

core  

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Digital and Remote Interventions for Musculoskeletal Aging: Real-Time Muscle Strain Severity Detection Using Artificial Intelligence. [PDF]

Biosensors (Basel)
Fatima Z, Abdullah, Hafeez N, Téllez RQ, Ruiz MJT, Mejorada CGS, Mata-Rivera MF, Zagal-Flores R.   +7 more
europepmc   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Ferroptosis and NMDA Receptor Activity in Alzheimer's Disease: Implications for Amyloid Pathology and P-Glycoprotein Regulation. [PDF]

Drug Dev Res
Salunkhe J, Ugale V.
europepmc   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Assessment of Myocardial Iron Overload and Strain Abnormalities in Pediatric β-Thalassemia Using Multiparametric CMR. [PDF]

Diagnostics (Basel)
Awadi R, Benameur N, Deriche M, Fraj IB, Boukhriba S, Taieb AB, Ouedreni M, Labidi S.   +7 more
europepmc   +1 more source