Results 51 to 60 of about 2,267,017 (307)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
This paper addresses the problem of monitoring online a non-stationary process to detect abrupt changes in the process mean value. Two main challenges are addressed: First, the monitored process is nonstationary; i.e., naturally changes over time and it ...
Karim Tout +2 more
doaj +1 more source
This work is part of a research project aimed at studying potential sorbents for CO2 capture. The main parameters characterising the adsorption process of zeolite 13X were derived with the aim of overcoming the limits of experimental analysis and thus ...
Alessio Caravella +5 more
doaj +1 more source
Quantum study of information delay in electromagetically induced transparency [PDF]
Using electromagnetically induced transparency (EIT), it is possible to delay and store light in atomic ensembles. Theoretical modelling and recent experiments have suggested that the EIT storage mechanism can be used as a memory for quantum information.
B. C. Buchler +7 more
core +2 more sources
The "Spiralia" represent one of the three major clades of bilaterian metazoans. Though members of this clade exhibit tremendous diversity in terms of their larval and adult body plans, many share a highly conserved early pattern of development involving a stereotypic cleavage program referred to as spiral cleavage.
openaire +3 more sources
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Internet enabled modelling of extended manufacturing enterprises using the process based techniques [PDF]
The paper presents the preliminary results of an ongoing research project on Internet enabled process-based modelling of extended manufacturing enterprises.
Cheng, K, Popov, Y
core +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Sediment and Radioactivity Transport in the Bohai, Yellow, and East China Seas: A Modeling Study
This paper is concerned with the development of a radionuclide dispersion model for the nuclear power plants in the Bohai, Yellow, and East China seas (BYECS) characterized by high turbidity and multi-scale circulations, focusing on the comparison of ...
Igor Brovchenko +6 more
doaj +1 more source
On Engineering Support for Business Process Modelling and Redesign [PDF]
Currently, there is an enormous (research) interest in business process redesign (BPR). Several management-oriented approaches have been proposed showing how to make BPR work. However, detailed descriptions of empirical experience are few.
Ferreira Pires, L. +3 more
core +4 more sources

