Results 91 to 100 of about 178,262,628 (263)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
, 2007 The purpose of this paper is to describe the influence over the public company which the internal control exerts focusing on the viewpoint that is the cost and the system in Japan, and shows that to implement the internal control like a cost ...
小野, 哲
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
The Internal Control System of Universitas Klabat Indonesia: An Assessment [PDF]
, 2009 This study assessed the Internal Control system in Universitas Klabat, Manado-Indonesia, Internal Control itself is a process, affected by an entity's board of directors, management and other personnel, designed to provide reasonable assurance regarding ...
Sibilang, Linne
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ENHANCING ASSETS' PROTECTION THROUGH AN ADEQUATE MONITORING OF INTERNAL CONTROL SYSTEM BY INTERNAL AUDIT [PDF]
Annals of the University of Oradea: Economic Science, 2011 The assets are established into a company as very important and strategic resources that are contributing at the creation of the needed premises to conduct the daily-basis activity and also to reach present and future planned objectives.
Dan Eugen Cosmin
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
PERSPECTIVES OF INTERNAL CONTROL SYSTEM [PDF]
, 2012 This paper which looked at the concept of internal control including its classification into financial and administrative forms, was anchored on the agency theory.
UDEH, Sergius Nwannebuike
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The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
CGIAR System Internal Audit Function Strategy
, 2018 This document sets out Internal Audit Function's vision, mission, value proposition, objectives, and the strategies to achieve the objectives.
CGIAR System Organization
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