Results 41 to 50 of about 4,990,437 (299)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Elements of system of internal control of insurance companies

Ученые записки Российской академии предпринимательства, 2021
In the article general-theoretical aspects of the economic relations in the sphere of insurance as link of a financial system of the country from a position of performance by insurance of control function are investigated, their complexity is disclosed ...
N. V. Zhuravleva, D. V. Bobyliov
doaj  

Thermoeconomic approach for the analysis of control system of energy plants [PDF]

, 2012
In this paper a thermoeconomic approach is applied to the dynamic model of a Power System in order to investigate the effects of the control system on the primary energy consumption and on the economic costs of the product.
Baccino, Bejan, El-Sayed, Giorgia Baccino, Hin, Larson, Lozano, Lozano, Rancruel, Reini, Shinskey, Verda, Verda, Vittorio Verda, Wang   +14 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

METHODOLOGICAL ASPECTS OF THE INTERNAL CONTROL SYSTEM FORMATION

Статистика и экономика, 2016
The methodological aspects of the internal control system formation are stated in the article. The great attention is focused on the problems of financial statements misrepresentation. The basic principles and structure of the internal control system are
Larisa I. Egorova, Elizaveta S. Sokolova, Galina V. Shadrina   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Output tracking via sliding modes in causal systems with time delay modeled by higher order pade approximations [PDF]

, 2006
Output tracking in a SISO causal uncertain nonlinear system with an output subject to a time delay is considered using sliding mode control. A higher order Pade approximation to a delay function with a known time delay is used to construct a model of a ...
Kosiba, E.A., Liu, G., Shtessel, Y.B., Zinober, A.S.I.   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dampak Sistem Pengendalian Internal Terhadap Penagihan Piutang Di Kota Bandung

Publica, 2018
This research is in the background behind the problems of Bandung City, which for the past five years still have a reasonable opinion with exceptions, one of the reasons is the high level of accounts receivable at the Bandung City Financial and Asset ...
Khaerul Umam, Angga Eka Pratama
doaj   +1 more source