Results 41 to 50 of about 404,025 (298)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
“BEYOND THE GDP” - THROUGH THE ENVIRONMENTAL ACCOUNTS [PDF]
In order to build a sustainable economic society with a lowenvironmental impact, the private sector and the general government must identify and implement active or voluntary tools capable of influencing the carrying out of the socio-economic activities ...
Daniela ŞTEFĂNESCU +2 more
doaj
Modelling consumption on the basis of the complete system of national accounts in Serbia - the wealth effect [PDF]
System of National Accounts (SNA) data on the financial and non-financial assets of the household sector are not currently being compiled by official statistics in Serbia, but this situation will change on the path of convergence to the ...
Jovanović Ivana
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Methodology of Estimating “Financial” Margins and their Capturing in the System of National Accounts [PDF]
Margins on buying and selling transactions, or simply “financial” margins, form one part of the complex system of national accounts. These financial services in acquiring and disposing of financial assets and liabilities on financial markets constitute ...
Jana Kramulová +2 more
doaj
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
NATIONAL ACCOUNTS OF ROBINSON ́S ECONOMY [PDF]
The system of national accounts provides data for economic analysis, especially analysis of business cycle. While properties of time series are continually under discussion, much less formation and predicative ability of the aggregates. Aim of this paper
Vaclav Rybacek
core
International Comparisons: Issues of Methodology and Practice [PDF]
The article discusses the methodology and organization of statistical observation of the level of countries’ economic development. The theoretical basis of international comparisons is singled out and on its basis the comparative evaluation of ...
Serova Irina A.
doaj

