Results 141 to 150 of about 378,371 (301)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

IS RUSSIA READY FOR THE INTRODUCTION OF THE NATIONAL REFERENCE PRICING SYSTEM?

open access: yesФармакоэкономика, 2015
the analysis of foreign pricing and drug supply public funding systems (or a so-called drug reimbursement) shows a substantial variety and presence of national peculiarities; however the majority of the developed foreign countries apply reference pricing.
V. V. Omelyanovskiy
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Referencing in fiber optic sensing systems [PDF]

open access: yes
Different techniques to account for losses induced by the environment on signals in intensity modulation fiber optic sensing systems are described and ...
Adamovsky, Grigory
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

CATALOGUING BAROQUE AZULEJO FRAMES. A PROJECT IN PROGRESS

open access: yesArt is on, 2016
The present article focuses on the cataloguing Baroque azulejo frames and aims to explain the methodology of the project as well as the expected results. I will discuss the importance of cataloguing and the system used – Az Infinitum – Azulejo Indexation
Rosário Salema de Carvalho
doaj  

mSpace meets EPrints: a Case Study in Creating Dynamic Digital Collections

open access: yes, 2006
In this case study we look at issues involved in (a) generating dynamic digital libraries that are on a particular topic but span heterogeneous collections at distinct sites, (b) supplementing the artefacts in that collection with additional information ...
Carr, Leslie A.   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An Ontology-based Referencing of Actors, Operations and Resources in eLearning Systems

open access: yes, 2004
We explore some of the multiple relationships between two very active research fields in eLearning and Knowledge Management research: educational modeling languages and ontologies. Our previous research projects in the last 10 years have shown the central importance of the association between the learning activities and the knowledge and skills that ...
Paquette, Gilbert, Rosca, Ioan
openaire   +1 more source

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