Results 161 to 170 of about 4,031,631 (301)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Semandaq: a data quality system based on conditional functional dependencies

, 2008
We present SEMANDAQ, a prototype system for improving the quality of relational data. Based on the recently proposed conditional functional dependencies (CFDs), it detects and repairs errors and inconsistencies that emerge as violations of these ...
Fan, Wenfei; id_orcid, Geerts, Floris, Jia, Xibei   +2 more
core  

Philippine Performance Evaluation and Assessment Scheme (PPEAS): Experiences in Newborn Screening System Quality Improvement. [PDF]

Int J Neonatal Screen, 2020
Padilla CD, Therrell BL, Panol KAR, Suarez RCN, Reyes MEL, Jomento CM, Maceda EBG, Lising JAC, Beltran FDE, Orbillo LL.   +9 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Behavioral determinants of continued use of Islamic FinTech: The moderating role of service and system quality. [PDF]

PLoS One
Alsmadi AA.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Application of integrative information system improves the quality and effectiveness of cancer case management

, 2015
Pei-Yi Lee,1,2 Tsue-Rung Chang11Department of Nursing, MacKay Memorial Hospital, Taipei, Taiwan; 2Department of Nursing, MacKay Medical College, Taipei, TaiwanAbstract: Cancer case management provides consecutive care during the entire process through ...
Lee PY, Chang TR
core  

Moderating influence of artificial intelligence capability between business intelligence system and decision-making quality in banking industry

Decision Science Letters
This paper examined the impact of Business Intelligence Systems (BIS) on decision-making quality among top-level management in the Jordanian banking sector, with Artificial Intelligence Capability as a moderating variable, to enhance understanding of the
Ibrahim A. Abu-AlSondos
doaj   +1 more source

Optimizing adolescent HIV care: a review of EMR system quality for clinical monitoring in Zambia. [PDF]

Front Public Health
Moomba K, Van Wyk B.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source