Results 191 to 200 of about 3,339,697 (253)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Digitizing death reporting in Zambia: evaluation of a mobile-based civil registration system. [PDF]

Glob Health Action
Odhiambo CO, Katama EN, Munkombwe B, Mwango C, Moyo S, Mapoma CC.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Advancing the service-oriented transition of smart cities: Evaluating the intelligent approval quality. [PDF]

PLoS One
Wang J, Wang Y.
europepmc   +1 more source

Reassessing the public health value of regional cancer registries in the era of Japan's National Cancer Registry: a learning health system perspective. [PDF]

Front Oncol
Narimatsu H, Watanabe K, Chei CL, Nakamura S.   +3 more
europepmc   +1 more source

Construction of a quality evaluation index system for nutrition nursing clinics based on the Donabedian model. [PDF]

Front Nutr
Zeng X, Jiang Y, Liu H, Huang Y, Chen X, Li A, Gu Y.   +6 more
europepmc   +1 more source