Results 81 to 90 of about 4,031,631 (301)

Quality Management System

open access: yesJournal of Clinical and Biomedical Sciences, 2021
Subhashish Das
doaj   +1 more source

Factors Influencing the Adoption of Domestic Messengers by Iranian Users [PDF]

open access: yesمطالعات رسانه‌های نوین
This study aimed to investigate the factors affecting the adoption of domestic messengers by Iranian users. The research was descriptive-causal in nature and employed a survey strategy.
zahra pourjoupari   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Edge Detection Techniques for Quantifying Spatial Imaging System Performance and Image Quality [PDF]

open access: yes, 2019
Measuring camera system performance and associating it directly to image quality is very relevant, whether images are aimed for viewing, or as input to machine learning and automated recognition algorithms.
Oliver van Zwanenberg   +7 more
core   +1 more source

WhatsApp groups: The nexus between retention, reciprocity, and user satisfaction

open access: yesFrontiers in Education
High dropout rates in higher education pose a significant challenge, prompting a need for effective retention strategies. Research shows promoting students’ engagement as key factor in retention.
Ismail Mohamed Ali   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

System quality, information quality, perceived usefulness, and ease of use as determinants of intention to continue using a Digital Accounting System among Jordanian SMEs

open access: yesEngineering Management in Production and Services
This study aims to investigate the determinants of the intention to continue using digital accounting systems (ICU-DAS) among Jordanian small and medium-sized enterprises (SMEs).
Alsqour Moh’d   +4 more
doaj   +1 more source

Conceptualization of the Factors Affecting the Quality of Mobile Health Services of Active SMEs in Healthcare System [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2014
Development of new technologies, particularly information technology (IT) has a great impact on the health care area and the quality of life style.
Mohammad Meigounpoory   +2 more
doaj  

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