Results 111 to 120 of about 19,511,736 (306)
Modern trends in knowledge representation and expert system technology
Le Matematiche, 1988 We will not be concerned with hardware aspects but we will discuss the present state of methodological concepts and software tools. Our main examples stem from the research activities at the Computer Science Department of the University of Kaiserslautern.
Klaus Nökel, Michael M. Richter
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2011 The utility of tones spaces based on tone productions can be judged on the degree to which they (i) differentiate tone productions and (ii) predict tone perception. Here based on a production corpus, 5 different 2-dimensional tone spaces are constructed.
Attina, Virginie (R14534) +3 more
core
DISCOURSE REPRESENTATION OF HOMOSEXUALITY IN THE SYSTEM DSM IV
Collectivus: Revista de Ciencias Sociales, 2015 The objective of this study is to highlight the construction and discursive significance that the DSM IV system gives to the homosexuality, considering that the meaning alludes to the internal content of the speech and the significance concerns the ...
Fernanda Téllez Vega
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
University of Texas System Annual Financial Report [PDF]
, 2013 Combined annual financial report of the entire University of Texas System for fiscal year 2013, including information about system-level administration and financial statements as well as reports from the institutions within the larger ...
University of Texas System
core
A study of the interrelationship of the integral characteristics of representation [PDF]
Психологическая наука и образование (2007. Online), 2015 The article raises the issue of representation, indicating that multi-dimensional representation as a psychological phenomenon requires consideration in different coordinate systems.
Peskov V.P.,
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source