Results 51 to 60 of about 6,359,946 (309)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Systematic Reviews, 2019 BackgroundHere, we outline a method of applying existing machine learning (ML) approaches to aid citation screening in an on-going broad and shallow systematic review of preclinical animal studies.
Alexandra Bannach‐Brown +6 more
semanticscholar +1 more source
Sequencing accuracy and systematic errors of nanopore direct RNA sequencing
bioRxiv, 2023 Background Direct RNA sequencing (dRNA-seq) on the Oxford Nanopore Technologies (ONT) platforms can produce reads covering up to full-length gene transcripts, while containing decipherable information about RNA base modifications and poly-A tail lengths.
Liu-Wei Wang +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Heat Exchange between Thermometer Well and Pipe Wall in Natural Gas Metering Systems
Energy Engineering and Control Systems, 2015 This paper deals with the accuracy of gas flow temperature measurement in natural gas metering systems. The effect of heat exchange between thermometer well and the pipe wall on the accuracy of gas flow temperature measurement is investigated.
Roman Fedoryshyn, Fedir Matiko
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Earth and Space ScienceThe findings from the Second Earth Orientation Parameters Prediction Comparison Campaign (2nd EOP PCC) suggest that integrating effective angular momentum (EAM) is vital for enhancing the accuracy of polar motion (PM) predictions. Building on Dill et al.
Wei Miao +3 more
doaj +1 more source
Active Suppression of Differential Light Shift Drift in an Atom Gravimeter
SensorsDifferential light shift (DLS) is an important error term that limits the atom interferometer’s measurement precision, especially for the case of the electro-optic modulator (EOM)-based scheme, where multiple laser sidebands exist, and their ratios are ...
Wei-Hao Xu +11 more
doaj +1 more source
Adjustment and testing comparison of absolute gravimeters in November 2013
Geoinformatics FCE CTU, 2017 This paper is focused on a comparison measurement processing of absolute gravimeters in 2013. The comparison deals with a number of various types of absolute gravimeters and includes also an absolute gravimeter from Geodetic observatory Pecný ...
Alena Pešková, Martin Štroner
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source