Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Methodology Used to Assess Acceptability of Oral Pediatric Medicines: A Systematic Literature Search and Narrative Review [PDF]
Punam Mistry +2 more
openalex +1 more source
Systematic literature review on search based software testing [PDF]
The use of random search is very poor at finding solutions when those solutions occupy a very small part of the overall search space. Test data may be found faster and more reliably if the search is given some guidance. This work is a paper that explains
Baharom, Salmi +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The NICE search filters for treating and managing COVID-19: validation in MEDLINE and Embase (Ovid)
Objective: In this paper we report how the United Kingdom's National Institute for Health and Care Excellence (NICE) search filters for treating and managing COVID-19 were validated for use in MEDLINE (Ovid) and Embase (Ovid).
Paul Levay, Amy Finnegan
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Professionals' views on the justification for esophageal adenocarcinoma screening: A systematic literature search and qualitative analysis. [PDF]
Sijben J +5 more
europepmc +1 more source
Correction: Web-Based Software Tools for Systematic Literature Review in Medicine: Systematic Search and Feature Analysis [PDF]
Kathryn Cowie +4 more
openalex +1 more source
Corticosteroid Administration to Prevent Complications of Anterior Cervical Spine Fusion: A Systematic Review. [PDF]
Study Design: Systematic review. Objectives: Anterior cervical approach is associated with complications such as dysphagia and airway compromise. In this study, we aimed to systematically review the literature on the efficacy and safety of corticosteroid
Abedi, Aidin +5 more
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source

