Results 211 to 220 of about 6,467,255 (355)

Epidemiology of Musculoskeletal Injuries Among Climbers-A Systematic Review. [PDF]

J Funct Morphol Kinesiol
Zieliński J, Grygorowicz M, Lewandowski J.   +2 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Patients' experiences of video consultations: A qualitative systematic review. [PDF]

Digit Health
Ärlebrant L, Schimmer R, Edin-Liljegren A.   +2 more
europepmc   +1 more source

Systematic Review of Veterans' Coping Strategies: How Can Rural Veterans Improve Their Quality of Life?

, 2016
Tracey Marie Barnett, Alexa Smith‐Osborne, Freda Barnett-Braddock   +2 more
openalex   +2 more sources

Impact of Vitamin D Deficiency on Reproductive Outcome in Infertile Anovulatory Women with Polycystic Ovary Syndrome: A Systematic Literature Review

, 2020
Yasmine Abuzeid
openalex   +1 more source

Distribution of High Risk Human Pappiloma Virus Genotypes Among Women with Cervical Cancer in East Africa: Systematic Review [PDF]

, 2019
Matifan Dereje Olana
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Necrotising enterocolitis biomarkers: a systematic review. [PDF]

Front Pediatr
Faizan MA, Khalid I, Yeo A, Fadel MM, Mcmahon A, Gavigan P, O'Neill S, Isweisi E, Semova G, Roche EF, Branagan A, Meehan J, Molloy EJ.   +12 more
europepmc   +1 more source

PND8 A SYSTEMATIC LITERATURE REVIEW OF EFFICACY AND SAFETY OF DISEASE MODIFYING THERAPIES (DMTS) IN SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS [PDF]

, 2019
Deepika Thakur, Vivek Khurana, Michel Kroes, Nicholas Adlard   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source