Results 241 to 250 of about 3,732,762 (303)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The Effect of Family Voice Interventions on Delirium Incidence and Duration in Adult ICU Patients: A Systematic Review and Meta-Analysis. [PDF]

open access: yesNurs Crit Care
Peschel E   +10 more
europepmc   +1 more source

Near-field and far-field exposures to radiofrequency electromagnetic fields and cancer risks in humans: a protocol for an umbrella review of epidemiological studies. [PDF]

open access: yesSyst Rev
Ziegler JL   +14 more
europepmc   +1 more source

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