Results 91 to 100 of about 4,238,138 (272)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Abscisic acid modulates salicylic acid biosynthesis for systemic acquired resistance in tomato

open access: yes, 2017
Among the regulatory mechanisms of systemic acquired resistance (SAR) in tomato, antagonistic interaction between salicylic acid (SA) and abscisic acid (ABA) signaling pathways was investigated. Treatment with 1,2-benzisothiazol-3(2H)-one1,1-dioxide (BIT)
Yasuko Okumura   +3 more
core   +1 more source

The Role of Ethylene in Systemic Acquired Resistance in Moss [PDF]

open access: yes, 2016
The moss species Physcomitrella patens and Amblystegium serpens were used to categorize the effects of the phytohormone ethylene in the plant-pathogen response mechanism systemic acquired resistance (SAR) in non-vascular plants.
Williams, Keiffer
core   +1 more source

Arabidopsis auxin mutants are compromised in systemic acquired resistance and exhibit aberrant accumulation of various indolic compounds [PDF]

open access: yes, 2010
Systemic acquired resistance is a widespread phenomenon in the plant kingdom that confers heightened and often enduring immunity to a range of diverse pathogens.
Grant, Murray   +7 more
core   +1 more source

Table_8_Protein Phosphorylation Changes During Systemic Acquired Resistance in Arabidopsis thaliana.XLSX

open access: yes, 2021
Systemic acquired resistance (SAR) in plants is a defense response that provides resistance against a wide range of pathogens at the whole-plant level following primary infection.
Wei Ding (690)   +7 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Table_10_Protein Phosphorylation Changes During Systemic Acquired Resistance in Arabidopsis thaliana.XLSX

open access: yes, 2021
Systemic acquired resistance (SAR) in plants is a defense response that provides resistance against a wide range of pathogens at the whole-plant level following primary infection.
Wei Ding (690)   +7 more
core   +1 more source

The control effect and induced disease resistance mechanism of Bacillus tequilensis on wheat powdery mildew

open access: yesBiological Control
Blumeria graminis f. sp. Tritici causes wheat powdery mildew (WPM) and severe wheat damage worldwide. To prevent WPM and emerging chemical fungicide resistance, researchers investigated the control effectiveness and induced disease resistance mechanisms ...
Qiuyan Bi   +5 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Table_1_Protein Phosphorylation Changes During Systemic Acquired Resistance in Arabidopsis thaliana.XLSX

open access: yes, 2021
Systemic acquired resistance (SAR) in plants is a defense response that provides resistance against a wide range of pathogens at the whole-plant level following primary infection.
Wei Ding (690)   +7 more
core   +1 more source

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