Results 181 to 190 of about 197,355 (287)

The Role of Ethylene in Systemic Acquired Resistance in Moss

, 2016
The moss species Physcomitrella patens and Amblystegium serpens were used to categorize the effects of the phytohormone ethylene in the plant-pathogen response mechanism systemic acquired resistance (SAR) in non-vascular plants.
Williams, Keiffer
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Systemic acquired resistance inducing chemicals mitigate black scurf disease in potato by activating defense-related enzymes. [PDF]

PeerJ
Buswal MK, Punia R, Kumar M, Tiwari RK, Lal MK, Kumar R.   +5 more
europepmc   +1 more source

Inducible biosynthesis and immune function of the systemic acquired resistance inducer N-hydroxypipecolic acid in monocotyledonous and dicotyledonous plants. [PDF]

J Exp Bot, 2020
Schnake A, Hartmann M, Schreiber S, Malik J, Brahmann L, Yildiz I, von Dahlen J, Rose LE, Schaffrath U, Zeier J.   +9 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Epidemiology and management of Fusarium wilt of Eucalyptus camaldulensis through systemic acquired resistance. [PDF]

PeerJ
Ahmad I, Mazhar K, Atiq M, Khalaf AK, Rashid MHU, Asif M, Ahmed S, Adil Z, Fayyaz A, Al-Sadoon MK, Al-Otaibi HS.   +10 more
europepmc   +1 more source

The plant cuticle regulates apoplastic transport of salicylic acid during systemic acquired resistance. [PDF]

Sci Adv, 2020
Lim GH, Liu H, Yu K, Liu R, Shine MB, Fernandez J, Burch-Smith T, Mobley JK, McLetchie N, Kachroo A, Kachroo P.   +10 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

H₂O₂ sulfenylates CHE, linking local infection to the establishment of systemic acquired resistance. [PDF]

Science
Cao L, Karapetyan S, Yoo H, Chen T, Mwimba M, Zhang X, Dong X.   +6 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source