Results 141 to 150 of about 6,373,239 (386)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Associations between Systemic and Dental Diseases in Elderly Korean Population

Medicina
Background and Objectives: Modernization and population aging have increased the prevalence of systemic diseases, such as diabetes and hypertension, which are often accompanied by various dental diseases.
Se Hoon Kahm, SungEun Yang
doaj   +1 more source

Association Analysis of Polymorphisms in Lumican Gene and Systemic Lupus Erythematosus in a Taiwan Chinese Han Population [PDF]

, 2011
Pei-Chun Chang, Yi Chen, MING-TSONG LAI, Heng-Yuan Chang, Chung‐Ming Huang, Hsin-Ping Liu, Wei‐Yong Lin, Chih‐Ho Lai, Jim Jinn‐Chyuan Sheu, Fuu‐Jen Tsai   +9 more
openalex   +1 more source

Dementia and Primary-Care Health Measures:Hearing, Gait, and Markers of Inflammation [PDF]

, 2015
Dementia is a syndrome associated with declining cognitive function that has a variety of types and causes, and is encountered frequently in general medical practice. Researchers are actively exploring possible risk factors for dementia. The St.
Lindgren, Elsa
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Joint association of the inflammatory marker and cardiovascular-kidney-metabolic syndrome stages with all-cause and cardiovascular disease mortality: a national prospective study

BMC Public Health
Background Cardiovascular-kidney-metabolic (CKM) syndrome and systemic inflammation significantly contribute to mortality. However, the joint associations of CKM stages and systemic inflammation with all-cause and cardiovascular disease (CVD) mortality ...
Yifei Cao, Wenfeng Wang, Shidong Xie, Yanfang Xu, Zishan Lin   +4 more
doaj   +1 more source

Associations of Raynaud's Phenomenon in Juvenile Onset Systemic Lupus Erythematosus

Van Tıp Dergisi
INTRODUCTION: Raynaud's phenomenon (RP) is associated with mild disease in adults with systemic lupus erythematosus (SLE). Although RP is more frequently reported in juvenile onset SLE (jSLE) clinical associations were not studied.
Özge Baba, Hakan Kısaoğlu, Mukaddes Kalyoncu   +2 more
doaj   +1 more source

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus [PDF]

, 2007
Amr H. Sawalha, Kenneth M. Kaufman, Jennifer A. Kelly, Adam J. Adler, Teresa Aberle, J Kilpatrick, Edward K. Wakeland, Q-Z Li, Amy E. Wandstrat, David R. Karp, Judith A. James, Joan T. Merrill, Peter E. Lipsky, John B. Harley   +13 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival [PDF]

, 2018
Päivi Sirniö, Juha P. Väyrynen, Kai Klintrup, Jyrki Mäkelä, Toni Karhu, Karl‐Heinz Herzig, Ilkka Minkkinen, Markus J. Mäkinen, Tuomo J. Karttunen, Anne Tuomisto   +9 more
openalex   +1 more source