Results 161 to 170 of about 6,373,239 (386)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery [PDF]

, 2007
Aziz Momin, Narbeh Melikian, Stephen B. Wheatcroft, David Grieve, Lindsay C.H. John, Ahmad El Gamel, Michael Marrinan, Jatin Desai, C Driver, Roy Sherwood, Ajay M. Shah, Mark T. Kearney   +11 more
openalex   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Systemic Inflammation Mediates the Associations Between Abdominal Obesity Indices and Lung Function Decline in a Chinese General Population

Diabetes, Metabolic Syndrome and Obesity, 2020
Heng He, 1, 2 Bin Wang, 1, 2 Min Zhou, 1, 2 Limin Cao, 1, 2 Weihong Qiu, 1, 2 Ge Mu, 1, 2 Ailian Chen, 1, 2 Shijie Yang, 1, 2 Weihong Chen 1, 2 1Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College ...
He H, Wang B, Zhou M, Cao L, Qiu W, Mu G, Chen A, Yang S, Chen W   +8 more
doaj  

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection [PDF]

, 2016
Aksoy, Alanen, Ascherio, Ayatollahi, Banez, Basch, Bergh, Berrington de Gonzalez, Borgermann, Bosch, Carter, Catalona, Chen, Elgamal, Fan, Fedewa, Grinstein, Hasui, Heidenreich, Joshi, Kadayifci, Kadayifci, Kilic, Krystyna, Kuller, Kutok, Lilja, Luzuriaga, Malavaud, Mandel, Moyer, Olsson, Oremek, Rickinson, Rubertone, Sfanos, Silverberg, Sindhwani, Smith, Stamey, Sutcliffe, Sutcliffe, Sutcliffe, Tchetgen, Whitaker, Whittemore, Wolf   +46 more
core   +2 more sources

Associating Systems [PDF]

Nature, 1968
openaire   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Exposome-wide association study of environmental toxicants and periodontitis among United States adults

Ecotoxicology and Environmental Safety
Objectives: To systematically evaluate associations between environmental toxicants and periodontitis and to quantify the mediating role of systemic inflammatory biomarkers. Methods: We extracted data from National Health and Nutrition Examination Survey
Xixi Dong, Xuejing Zhong, Jinmei Wu, Yichen Lin, Baochang He, Jing Wang, Fuhua Yan, Yanfen Li, Lingjun Yan, Fa Chen   +9 more
doaj   +1 more source

Mannose-binding Lectin Expression Genotype in Pediatric-onset Systemic Lupus Erythematosus: Associations with Susceptibility to Renal Disease and Protection Against Infections [PDF]

, 2011
Yi‐Chan Tsai, Kou-Wei Yeh, Tsung‐Chieh Yao, Yulin Huang, Ming‐Ling Kuo, Jing‐Long Huang   +5 more
openalex   +1 more source