Results 101 to 110 of about 100,804 (312)

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

open access: yesAdvanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou   +6 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu   +13 more
wiley   +1 more source

The Single Supervisory Mechanism: the Building Pillar of the European Banking Union

open access: yesUniversity of Bologna Law Review, 2016
One of the lessons learned from the 2008 financial crisis is that when a bank in Europe goes into trouble the ensuing effects can reach far beyond the immediate threat to its depositors and shareholders.
Luigi Chiarella
doaj   +1 more source

Financial Reform and Banking Crises [PDF]

open access: yes
We examine the impact of various dimensions of financial reform on the likelihood of systemic and non-systemic banking crises. Using new financial reform measures for a large sample of developing and developed countries for the period 1973 to 2002, our ...
Choudhry Tanveer Shehzad, Jakob de Haan
core  

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

Banking Sector Systemic Risk in Selected Cenral European Countries. Review of: Bulgaria, Czech Republic, Hungary, Poland, Romania and Slovakia [PDF]

open access: yes
The paper is an attempt at a comparative overview of banking sector systemic risk in six Central European countries as of the end of 1997 concluding with some policy recommendations.
Stefan Kawalec
core  

Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

open access: yesAdvanced Science, EarlyView.
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song   +12 more
wiley   +1 more source

Early Warning Models for Systemic Banking Crises in Montenegro [PDF]

open access: yesEconomic and Business Review, 2013
The purpose of this research is to create an adequate early warning model for systemic banking crises in Montenegro. The probability of banking crisis occurrence is calculated using discrete dependent variable models, more precisely, estimating logit ...
Željka Asanović
doaj  

Options for Managing a Systemic Bank Crisis

open access: yesS.A.P.I.EN.S, 2009
The on-going financial crisis results not from a cyclical or managerial failure, but from a structural one: more than 96 other major banking crises occurred over the past 20 years, and these crashes have happened under very different regulatory systems and at different stages of economic development.
Lietaer, Bernard   +2 more
openaire   +1 more source

The Subprime Crisis and the European Banking Sector: the Renewal of Universal Banks? [PDF]

open access: yes
Since the 90's, European banks have sustained numerous structural disturbances. Their degree of integration combined with the universality of our institutions in the banking sector may then be an important factor to take into account in appreciating its ...
Elisabeth Paulet
core  

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