Systemic lupus erythematosus and hearing disorders: literature review and meta-analysis of clinical and temporal bone findings [PDF]
Objective: This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).
DI STADIO, Arianna, Ralli, Massimo
core +1 more source
Aspects Regarding the Innovative Conceptual Design for Children’s Recreational Areas
Conceptual design approaches the definition of an innovative concept design applied to a product intended for children’-=s recreational area, corresponding to a personal profile located around the age of childhood, namely aged 2 to 5.
Bogdan Bucur +3 more
doaj +1 more source
Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host [PDF]
Purpose: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival.
Clark, Jennifer +7 more
core +1 more source
A Traceable Integration of Soft Systems Methodology and Theory of Constraints–Thinking Processes for Stakeholder Conflict Resolution and Organizational Alignment [PDF]
Through a systemic intervention grounded in critical realism, this study integrates Soft Systems Methodology and the Theory of Constraints-Thinking Processes in a participatory inquiry to achieve stakeholder consensus and to design a conceptual model ...
Sasan Sepasi, Azim Zarei
doaj +1 more source
Systemic Exercise-Induced Hypoalgesia Following Isometric Exercise Reduces Conditioned Pain Modulation [PDF]
Objective Physically active individuals show greater conditioned pain modulation (CPM) compared with less active individuals. Understanding the effects of acute exercise on CPM may allow for a more targeted use of exercise in the management of pain. This
Alsouhibani, Ali +2 more
core +2 more sources
Local micro-networks for green transition of the wool supply chain
Italy’s inland areas face complex challenges such as depopulation, isolation and economic weakness. Through a research project conducted in Taranta Peligna (Chieti, IT), the paper aims to enhance the wool supply chain by adopting a systemic, co-design ...
Rossana Gaddi, Luciana Mastrolonardo
doaj +1 more source
Systemic Design: Two Canadian Case Studies
This paper introduces two novel applications of systemic design to facilitate a comparison of alternative methodologies that integrate systems thinking and design.
Alex Ryan, Mark Leung
doaj +1 more source
Embedding sustainability in design education: the case of design project on systemic changes for sustainable businesses based on upcycling [PDF]
Sustainable design education has become a prevalent practice in design education. Ramirez’s (2007) worldwide survey shows that the majority of the programmes have either compulsory or optional modules on sustainable design.
Sung, Kyungeun, Yoon, Jungkyoon
core
Target value design: using collaboration and a lean approach to reduce construction cost [PDF]
Target Costing is an effective management technique that has been used in manufacturing for decades to achieve cost predictability during new products development. Adoption of this technique promises benefits for the construction industry as it struggles
Christine Pasquire +12 more
core +1 more source
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source

