Results 131 to 140 of about 1,369,121 (264)

Evidence for microvesicle particles and platelet-activating factor as effectors for systemic effects of thermal burn injury. [PDF]

Front Immunol
Parackal AV, Fox RC, Umerani A, Park Y, Johnson RM, Zhang W, Xu Z, Smith AA, Rohan CA, Travers JB.   +9 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Toxicological Assessment of Cobalt-Chromium Dental Alloys: Ion Release, Cytotoxicity, and Possible Systemic Effects. [PDF]

Biol Trace Elem Res
Yahya AA, Hosny G, El-Banna SG, Alsakhawy SA.   +3 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Systemic Effects of Anabolic-Androgenic Steroid Abuse: A Case in Primary Care. [PDF]

Cureus
de Carvalho Vilarinho M, Cernadas J, Marques Ferreira M.   +2 more
europepmc   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Spatial mapping of dextran sodium sulphate-induced intestinal inflammation and its systemic effects. [PDF]

FASEB J
Adams L, Rasid O, Hulme H, Quon T, Burchmore R, Milling S, Goodwin RJA, Wall DM.   +7 more
europepmc   +2 more sources

Systemic Effects of Vascular Photobiomodulation on Early Macrophage Recruitment During Skeletal Muscle Repair. [PDF]

J Biophotonics
da Silva RLO, Malavazzi TCDS, Silva AS, Bussadori SK, Horliana ACRT, Nunes FD, Fernandes KPS, Rodrigues MFSD, Mesquita-Ferrari RA.   +8 more
europepmc   +1 more source

Systemic effects of oral tolerance in bone healing. [PDF]

Sci Rep, 2023
Costa BH, Rezende AK, Costa L, Neves GFM, Shimano AC, de Oliveira Penoni Á, Carvalho CR, Costa RA, de Alvarenga EC.   +8 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source