Results 101 to 110 of about 5,217 (255)

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

A synthetic community promotes macadamia growth via root‐microbe interactions and systemic plant responses

open access: yesiMetaOmics, EarlyView.
We employed an 18‐month pot experiment and an integrated multi‐omics approach to elucidate the potential mechanisms underlying synthetic community (SynCom)‐mediated macadamia growth promotion. SynCom inoculation enhanced soil nitrogen cycling and potential nutrient (e.g., iron) acquisition.
Xiaofang Yao   +5 more
wiley   +1 more source

Financial Development Under Economic Sanctions: Short‐Run Market Responses and Long‐Run Institutional Adjustment

open access: yesInternational Studies of Economics, EarlyView.
ABSTRACT This paper examines how the financial development of the target economy evolves under the long‐lasting economic sanctions, emphasizing the temporal patterns of the impact. Using panel data for 136 economies from 1980 to 2021 and an event‐study approach, we identified a temporal pattern that illustrates how economic sanctions exert a ...
Yu Jiang, Xue Meng
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos   +10 more
wiley   +1 more source

Systemic Functional Grammar in the Teaching of Reading Philosophical Texts in EAP

open access: yesThe ESPecialist, 2011
Systemic functional grammar (SFG) has been more and more used in different contexts and for different purposes as a tool to help us understand how languages are used to make meaning.
Orlando Vian Jr.
doaj  

Exploring Korean Counselors’ Meaning of Counseling Expertise: Focusing on Differences Between Intermediate and Advanced Counselors

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT This study examined how Korean counselors conceptualize counseling expertise across developmental stages. Using text mining of 70 counselors’ written responses, analyses included word frequency, semantic network, and CONCOR clustering. Both groups shared a lexical foundation, with performance competence, continuous learning, and diverse ...
GeonWoo Cho, GoEun Na, Nanseol Heo
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

Plasma Proteomic Profiling Identifies Candidate Biomarkers for Pancreatic Ductal Adenocarcinoma

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Using DIA‐based plasma proteomics followed by ELISA validation, we identified eight circulating proteins that were significantly elevated in patients with pancreatic ductal adenocarcinoma. These proteins reflect key tumor‐associated biological processes, including exocrine dysfunction and immune remodeling, and may serve as candidates for future multi ...
Lelang Xiang   +5 more
wiley   +1 more source

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