Results 41 to 50 of about 210,091 (214)

Sedentary behavior is associated with systemic immune-inflammation index and systemic inflammation response index levels: a cross-sectional analysis of the NHANES 2011–2018

Frontiers in Public Health
BackgroundSedentary behavior (SB), has been closely linked to numerous detrimental health effects. While the individual and combined impacts of such behaviors on immune-inflammatory responses remain ambiguous, innovative indices like the Systemic Immune ...
Xian Wu, Lin Zhong, Yuehong Hu, Lingying Ruan, Kaiyu Zhou, Hanmin Liu, Lina Chen   +6 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

The Role of Systemic Immune-Inflammation Index and Systemic Inflammation Response Index in the Diagnosis of Bell’s Palsy

Journal of Behçet Uz Children's Hospital
Objective: Recent studies showed that Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI) can be used as inflammatory markers.
Betül Öztürk, Raziye Merve Yaradılmış, Muhammed Mustafa Güneylioğlu, Ali Güngör, İlknur Bodur, Aytaç Göktuğ, Orkun Aydın, Meltem Akçaboy, Ergin Atasoy, Can Demir Karacan, Nilden Tuygun   +10 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Evaluation of pseudoexfoliation syndrome patients with systemic immune indexes

BMC Ophthalmology
Purpose The aim of this study was to investigate the level of peripheral blood systemic immune indexes in pseudoexfoliation syndrome (PXS) patients and to compare the results with healthy controls.
Ömer Özer, Emin Serbülent Güçlü
doaj   +1 more source

Relationship between systemic immune inflammation index and systemic inflammation response index values and prognosis in patients with burns

Medicine Science
To determine the relationship between systemic immune inflammation index (SyII) and systemic inflammation response index (SyIRI) values and prognosis in adult and pediatric cases treated for deep partial thick and full thick burns.
Serap Samut Bulbul, Alper Ceylan, Metin Ocak, Selim Gorgum, Tolga Pamuk, Mesut Oterkus   +5 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Association between systemic immune-inflammation index and urinary incontinence: Evidence from the National Health and Nutrition Examination Survey

Journal of International Medical Research
Objective This study examined the association between the systemic immune-inflammation index and urinary incontinence subtypes using data from National Health and Nutrition Examination Survey 2007–2016.
Feike Ma, Zhi-Cheng Cong, Hao Zhang, Yi-Han Chen, Yi-Lun Cui, Yue Duan, Ting-Ting Tao   +6 more
doaj   +1 more source

Association Between Systemic Immune-Inflammation Index and Diabetic Depression

Clinical Interventions in Aging, 2021
Jie Wang,1 Depu Zhou,1 Zhijuan Dai,2 Xiaokun Li1 1Department of Endocrinology, Yanbian University Hospital, Yanji, Jilin, People’s Republic of China; 2Department of Endocrinology, The Second Affiliated Hospital of Wenzhou Medical University ...
Wang J, Zhou D, Dai Z, Li X
doaj