Results 121 to 130 of about 362,549 (389)

Relationship between emergency presentation, systemic inflammatory response, and cancer-specific survival in patients undergoing potentially curative surgery for colon cancer [PDF]

, 2009
Background Emergency presentation is recognized to be associated with poorer cancer-specific survival following curative resection for colorectal cancer.
Canna, Carstairs, Crumley, Donald C. McMillan, Du Clos, E. Fiona Leitch, Forrest, Franch-Arcas, Gibbs, Glen, Heys, Heys, Hole, John H. Anderson, Joseph E.M. Crozier, Leitch, Longo, Longo, McArdle, McArdle, McMillan, McMillan, McMillan, McMillan, McMillan, Nielsen, Nozoe, Paul G. Horgan, Phillips, Preston, Ruth F. McKee, Scott, Vermeire, Ytting   +33 more
core   +1 more source

Evaluation of pseudoexfoliation syndrome patients with systemic immune indexes

BMC Ophthalmology
Purpose The aim of this study was to investigate the level of peripheral blood systemic immune indexes in pseudoexfoliation syndrome (PXS) patients and to compare the results with healthy controls.
Ömer Özer, Emin Serbülent Güçlü
doaj   +1 more source

Predictive value of systemic immune-inflammation index for pathological complete response in patients receiving neoadjuvant immunochemotherapy for locally advanced esophageal cancer [PDF]

, 2023
Wu Han, Kai Weng, Peipei Zhang, Zhi-Nuan Hong   +3 more
openalex   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources

Systemic Immune-Inflammation Index and Systemic Inflammatory Response Index as Predictors of Mortality in ST-Elevation Myocardial Infarction

Journal of Clinical Medicine
(1) Background: The systemic inflammatory response index (SIRI; neutrophil count × monocyte/lymphocyte count), and the systemic immune-inflammation index (SII; platelet count × neutrophil count/lymphocyte count) are recently proposed biomarkers to assess
Federica Marchi, Nataliya Pylypiv, Alessandra Parlanti, Simona Storti, M. Gaggini, U. Paradossi, S. Berti, C. Vassalle   +7 more
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Prognostic importance of the systemic inflammatory index and the systemic inflammatory response index in COVID-19 patients

Emergency Care Journal
COVID-19 can cause a wide range of effects on patients, from asymptomatic cases to mortality. Many factors can affect the prognosis of the disease. Our study aims to evaluate the predictive power of the Systemic Inflammatory Index (SII) and Systemic ...
Alikemal Topal, Akif Yarkaç, Seyran Bozkurt Bozkurt, Çağrı Safa Buyurgan, Ataman Köse, Semra Erdoğan   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Systemic immunity-inflammation index and body mass index: A cross-sectional study

PLOS One
Background and aim The Systemic Immunity-inflammation Index (SII) is an emerging metric for assessing an individual’s immunological and inflammatory condition. Studies examining the relationship between SII and body mass index (BMI) are limited. This study aims to clarify the correlation between SII and BMI.
Wei Guo, Chongheng Zhang, Fang Cao, Xinxin Sun, Jian Li, Wenfeng Zhang   +5 more
openaire   +3 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source