Results 141 to 150 of about 362,549 (389)
Preoperative systemic immune-inflammation index predicts survival and recurrence in patients with resected primary pulmonary sarcomatoid carcinoma [PDF]
, 2021 Qingpeng Zeng +10 more
openalex +1 more source
Shift Work: Gut Health and Metabolic Disease [PDF]
, 2020 The number of people engaged in shift work continues to rise, and with it the research linking shift work to various diseases and conditions. Shift work changes the body’s sleeping patterns and circadian rhythms which has an effect on all parts of the ...
Lane, Hailey
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
BMC Musculoskeletal DisordersBackground Osteoarthritis (OA) is a degenerative and inflammatory joint disease caused by multiple factors, the underlying mechanisms of which are not fully understood. The systemic immune-inflammation index (SII) and systemic inflammation response index
Xiao-Jun Chen +11 more
doaj +1 more source
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis [PDF]
, 2016 TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative therapies for these diseases.
Barrios, Bibiana Elisabet +6 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
BMC GeriatricsBackground Chronic inflammation is increasingly recognized as a crucial contributor to sarcopenia pathogenesis, but accurate diagnosis remains a challenge.
Esra Cataltepe +6 more
doaj +1 more source
Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]
, 2017 Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco +6 more
core +2 more sources
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Systemic infections after acute stroke [PDF]
, 2008 After an acute stroke, systemic infection can complicate the recovery process and lead to a worse clinical outcome, including a higher risk of mortality.
Damian Jenkinson +11 more
core +1 more source