Results 141 to 150 of about 661,063 (353)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Impacts of Inflammatory Cytokines Variants on Systemic Inflammatory Profile and COVID-19 Severity

Journal of Epidemiology and Global Health
Background Cytokine storm is known to impact the prognosis of coronavirus disease 2019 (COVID-19), since pro-inflammatory cytokine variants are associated with cytokine storm.
XueJun Deng, Kai Tang, Zhiqiang Wang, Suyu He, Zhi Luo   +4 more
doaj   +1 more source

Surgical treatment of varicose veins reduces leg edema and generalized edema: Alleviating clinical symptoms throughout the body

Vascular Investigation and Therapy
Edema presents itself in two primary forms: generalized edema and localized edema. Previous studies suggest that varicose veins contribute to systemic edema. We investigated if treating them could alleviate symptoms elsewhere.
Shinji Tomita, Yutaka Koyama, Masahiro Inagaki, Satoki Ozoe   +3 more
doaj   +1 more source

Evaluation of derivatives impact to early systemic risk of Euro area

, 2020
Rima Žitkienė, Valdas Grigonis, Pavlo Burak   +2 more
openalex   +2 more sources

Thrombin generation potential is enhanced in systemic sclerosis: impact of selected endothelial biomarkers

, 2021
Piotr Kuszmiersz, Renata Pacholczak‐Madej, Angelika Siwiec, Magdalena Celińska‐Löwenhoff, Teresa Iwaniec, Joanna Kosałka-Węgiel, Lech Zaręba, Stanisława Bazan‐Socha, Jerzy Dropiński   +8 more
openalex   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Identifying and addressing the components of extreme physical-oceanographical events for improved risk management in coastal systems

Frontiers in Marine Science
Extreme physical-oceanographic events, such as marine heatwaves, fluvial floods, droughts and storm surges, have major impacts on local communities, economic sectors and ecosystems, and their frequency, intensity and duration increase due to climate ...
Eric P. Achterberg, Fabian Rackelmann, Ananya Ramesh, Jack O’Connor, Ovidio García-Oliva, Saranya Jayachandran, Viktoria Wichert, Xiangyu Li, Kaveh Purkiani, David M. Needham, Ingeborg Bussmann, Philipp Fischer, Achim Kopf, Carsten Lemmen, Jörn Peter Scharsack, Christian Siebert, Norbert Kamjunke, Inna M. Sokolova, Inna M. Sokolova, Holger Brix   +19 more
doaj   +1 more source

The Impact of Vitamin D on Cognitive Dysfunction in Mice with Systemic Lupus Erythematosus

, 2019
Lijun Yan, Ping Wu, Dongmei Gao, Jie Hu, Qian Wang, Nan-Fang Chen, Sheng-quan Tong, Rao Li, Jing Liu   +8 more
openalex   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

OP0251 THE EULAR SYSTEMIC SCLEROSIS IMPACT OF DISEASE (SCLEROID) SCORE – A NEW PATIENT-REPORTED OUTCOME MEASURE FOR PATIENTS WITH SYSTEMIC SCLEROSIS [PDF]

, 2020
Mike Oliver Becker, R. Dobrota, K. Fligelstone, A. Roennow, Yannick Allanore, Patrícia Carreira, L. Czirják, C. Denton, Roger Hesselstrand, Gunnel Sandqvist, Otylia Kowal‐Bielecka, Cosimo Bruni, M. Matucci Cerinic, Carina Mihai, Ana Maria Gheorghiu, Ulf Müller‐Ladner, Joe Sexton, Turid Heiberg, Oliver Distler   +18 more
openalex   +1 more source