[Systemic mastocytosis: bone impact].
Medicina, 2013 Systemic mastocytosis is a disease characterized by accumulation of mast cells in various organs of which the most affected is the skin. The bone impact of this disease is very rare and generally associated with the development of secondary osteoporosis with or without fractures.
Francisco R, Spivacow +2 more
openaire +1 more source
Inclusive governance in non-profit organisations [PDF]
, 2015 The study of private non-profit enterprises that offer general interest services is only at the start. The understanding of existing organisations resists an inclusive, public interest view of governance.
Borzaga, Carlo, Sacchetti, Silvia
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Corrigendum: Impact of modern systemic therapies and clinical markers on treatment outcome for metastatic melanoma in a real‐world setting [PDF]
, 2021 Isabelle Krakowski +6 more
openalex +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Structural integrity: Recognizing, measuring, and addressing systemic racism and its health impacts
EClinicalMedicine, 2021 Renée Boynton-Jarrett +2 more
doaj +1 more source
MODELLING THE DISTRIBUTIONAL IMPACTS OF AGRICULTURAL POLICIES IN DEVELOPING COUNTRIES: THE DEVELOPMENT POLICY EVALUATION MODEL (DEVPEM) [PDF]
The purpose of the Development Policy Evaluation Model (DEVPEM) is to provide an appropriate modelling structure for analysing the welfare and distributional implications of alternative agricultural policies in developing countries.
Brooks, Jonathan +3 more
core +1 more source