Results 221 to 230 of about 330,033 (304)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Association Between Systemic Inflammation Response Index and Large Hemispheric Infarction: Development of a Predictive Diagnostic Model - A Retrospective Study. [PDF]

J Inflamm Res
Jiao YX, Mu SZ, Kang B.
europepmc   +1 more source

Mechanotransducing Organic Electrochemical Diode for Crosstalk‐Inhibited Artificial Skin

Advanced Functional Materials, EarlyView.
An innovative approach is presented to a stretchable mechanotransducing diode that unifies rectification and tactile‐sensing functionality. This approach enables to fabricate the diode that maintains a large rectification ratio (5 × 102) at a high operational frequency (100 Hz).
Taeyeong Kim, Seunggoo Baek, Garrett Lecroy, Hyeongseok Choi, Wonjeong Suh, Woosung Cho, Alberto Salleo, Unyong Jeong   +7 more
wiley   +1 more source

L-shaped association of systemic inflammation response index with rheumatoid arthritis in U.S. adults: Evidence from NHANES 1999 to 2020. [PDF]

Medicine (Baltimore)
Zhao M, Zhang Z, Pang C, Liao T, Jiang D, Qunpei L, Luobu Z, Chen X.   +7 more
europepmc   +1 more source

Clinical significance of systemic inflammation response index and platelet–lymphocyte ratio in patients with adenocarcinoma of the esophagogastric junction and upper gastric cancer [PDF]

Tianyi Fang, Xin Yin, Yufei Wang, Lei Zhang, Shuo Yang, Xinju Jiang, Yingwei Xue   +6 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Association between systemic inflammation response index and atrial fibrillation in chronic obstructive pulmonary disease: a multicenter cross-sectional study. [PDF]

Front Med (Lausanne)
Xu H, Li T, Yang M, Zheng Y, Zhu X, Chen L, Zhao H.   +6 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Association between the systemic inflammation response index and mortality in cancer survivors based on NHANES 2001-2018. [PDF]

Sci Rep
Yang FR, Li HL, Hu XW, Sha R, Li HJ.
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source