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Systemic Lupus Erythematosus [PDF]

open access: yesClinical and Developmental Immunology, 2012
Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Anne Davidson   +3 more
  +12 more sources

Systemic lupus erythematosus [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2006
Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of autoantibodies directed against nuclear antigens. It is a multi-system disease, and patients can present in vastly different ways.
Anisur Rahman, Jessica J Manson
  +11 more sources

Systemic Lupus Erythematosus [PDF]

open access: yesCell, 1996
Systemic Lupus Erythematosus (SLE) of childhood is a complex and challenging disease which can occur at any age. Identification of disease early in it's course and aggressive, appropriate management leads to improved outcome for an individual child. The history of SLE indicates how much progress has been made in the last quarter century.
Marisa S. Klein-Gitelman   +1 more
openaire   +6 more sources

Cerebral Vein Thrombosis in the Antiphospholipid Syndrome: Analysis of a Series of 27 Patients and Review of the Literature

open access: yesBrain Sciences, 2021
(1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas   +9 more
doaj   +1 more source

Deucravacitinib, a Tyrosine Kinase 2 Inhibitor, in Systemic Lupus Erythematosus: A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesArthritis & Rheumatology, 2022
To assess the efficacy and safety of deucravacitinib, an oral, selective, allosteric inhibitor of TYK2, in a phase II trial in adult patients with active systemic lupus erythematosus (SLE).
Eric F Morand   +12 more
semanticscholar   +1 more source

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

open access: yesArthritis & Rheumatology, 2019
To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
M. Aringer   +63 more
semanticscholar   +2 more sources

Systemic lupus erythematosus with trisomy X: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2022
Background The cause of systemic lupus erythematosus is not completely clear so far, but the prevalence of systemic lupus erythematosus is significantly increased in people with additional X chromosomes.
Fang Luo, Qiao Ye, Jie Shen
doaj   +1 more source

Peritonitis as the first presentation of systemic lupus erythematous: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Systemic lupus erythematosus is an inflammatory disease affecting several organs. Serositis is one of the systemic lupus erythematosus presentations, but peritonitis is a relatively rare presentation.
Zahedin Kheyri   +2 more
doaj   +1 more source

Evaluation of Immune Response and Disease Status in Systemic Lupus Erythematosus Patients Following SARS–CoV‐2 Vaccination

open access: yesArthritis & Rheumatology, 2021
To evaluate seroreactivity and disease flares after COVID‐19 vaccination in a multiethnic/multiracial cohort of patients with systemic lupus erythematosus (SLE).
P. Izmirly   +28 more
semanticscholar   +1 more source

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