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Systemic Lupus Erythematosus [PDF]
Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Anne Davidson+3 more
+12 more sources
Systemic lupus erythematosus [PDF]
Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of autoantibodies directed against nuclear antigens. It is a multi-system disease, and patients can present in vastly different ways.
Anisur Rahman, Jessica J Manson
+11 more sources
Objectives To quantify global, regional and country-specific estimates of epidemiology of systemic lupus erythematosus (SLE). Methods Four databases were systematically searched, and a Bayesian hierarchical linear mixed model was constructed to estimate ...
Jingru Tian+4 more
semanticscholar +1 more source
Systemic Lupus Erythematosus [PDF]
Systemic Lupus Erythematosus (SLE) of childhood is a complex and challenging disease which can occur at any age. Identification of disease early in it's course and aggressive, appropriate management leads to improved outcome for an individual child. The history of SLE indicates how much progress has been made in the last quarter century.
Marisa S. Klein-Gitelman+1 more
openaire +6 more sources
EULAR recommendations for the management of systemic lupus erythematosus: 2023 update
Objectives To update the EULAR recommendations for the management of systemic lupus erythematosus (SLE) based on emerging new evidence. Methods An international Task Force formed the questions for the systematic literature reviews (January 2018–December ...
A. Fanouriakis+41 more
semanticscholar +1 more source
(1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas+9 more
doaj +1 more source
To assess the efficacy and safety of deucravacitinib, an oral, selective, allosteric inhibitor of TYK2, in a phase II trial in adult patients with active systemic lupus erythematosus (SLE).
Eric F Morand+12 more
semanticscholar +1 more source
Systemic lupus erythematosus with trisomy X: a case report and review of the literature
Background The cause of systemic lupus erythematosus is not completely clear so far, but the prevalence of systemic lupus erythematosus is significantly increased in people with additional X chromosomes.
Fang Luo, Qiao Ye, Jie Shen
doaj +1 more source
To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
M. Aringer+63 more
semanticscholar +2 more sources
Peritonitis as the first presentation of systemic lupus erythematous: a case report
Background Systemic lupus erythematosus is an inflammatory disease affecting several organs. Serositis is one of the systemic lupus erythematosus presentations, but peritonitis is a relatively rare presentation.
Zahedin Kheyri+2 more
doaj +1 more source