Results 1 to 10 of about 327,708 (302)

Age-related changes in Serum Growth Hormone, Insulin-like Growth Factor-1 and Somatostatin in System Lupus Erythematosus

open access: yesBMC Musculoskeletal Disorders, 2004
Background Systemic lupus erythematosus is an age- and gender-associated autoimmune disorder. Previous studies suggested that defects in the hypothalamic/pituitary axis contributed to systemic lupus erythematosus disease progression which could also ...
Malemud Charles J, Denko Charles W
doaj   +1 more source

The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus.

open access: yesArthritis & Rheumatism, 1996
OBJECTIVE To develop and perform an initial validation of a damage index for systemic lupus erythematosus (SLE). METHODS A list of items considered to reflect damage in SLE was generated through a nominal group process. A consensus as to which items to
D. Gladman   +21 more
semanticscholar   +1 more source

Serological comparison of systemic lupus erythematosus with neuropsychiatric lupus using synthetic nucleic acid antigens

open access: yesJournal of Translational Autoimmunity, 2020
Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by an irregular exchange between the central nervous system and the immune system, leading to the outbreak of neurological conditions with possible disabling effects ...
Sangita Khatri   +7 more
doaj   +1 more source

Antineutrophil Cytoplasmic Autoantibody-Negative Pauci-Immune Crescentic Glomerulonephritis in a Patient with Systemic Lupus Erythematosus

open access: yesCase Reports in Nephrology and Dialysis, 2022
Renal involvement in systemic lupus erythematosus is usually exhibited as lupus nephritis, which is a form of immune complex-mediated glomerulonephritis and one of the most severe organ manifestations of systemic lupus erythematosus.
Chee Eng Chan   +3 more
doaj   +1 more source

Fibrous histiocytoma as first presentation in systemic lupus erythematosus and sero-positive Sjögren's syndrome

open access: yesAmerican Journal of Ophthalmology Case Reports, 2018
Purpose: To describe a triad of fibrous histiocytoma, Systemic Lupus Erythematosus and Sero-positive Sjögren's Syndrome. Observations: This case was diagnosed first as bilateral fibrous histiocytoma of cheeks, which on further investigations proved to be
Abdullah Al-Mujaini   +2 more
doaj   +1 more source

Systemic Lupus Erythematosus (SLE) Therapy: The Old and the New

open access: yesRheumatology and Therapy, 2020
Despite recent improvements in the treatment of systemic lupus erythematosus (SLE), disease activity, comorbidities and drug toxicity significantly contribute to the risk of progressive irreversible damage accrual and increased mortality in patients with
F. Basta   +3 more
semanticscholar   +1 more source

Juvenile Systemic Lupus Erythematosus Presenting with Esophagitis and Severe Oral Mucositis

open access: yesCase Reports in Rheumatology, 2021
We present a case of a previously healthy adolescent female who developed severe oral mucositis and acute esophagitis as her presenting symptoms of juvenile systemic lupus erythematosus.
Emily Schildt   +2 more
doaj   +1 more source

Anifrolumab, an Anti–Interferon‐α Receptor Monoclonal Antibody, in Moderate‐to‐Severe Systemic Lupus Erythematosus

open access: yesArthritis & Rheumatology, 2017
To assess the efficacy and safety of anifrolumab, a type I interferon (IFN) receptor antagonist, in a phase IIb, randomized, double‐blind, placebo‐controlled study of adults with moderate‐to‐severe systemic lupus erythematosus (SLE).
R. Furie   +9 more
semanticscholar   +1 more source

Migraine In Systemic Lupus Erythematosus in Rheumatological outpatients unit

open access: yesمجله كليه طب الكندي, 2019
Background: Migraine is common in systemic lupus erythematosus.It is a significant source of patient disability. Objective: To determine the rate of migraine in patients with systemic lupus erythematosus, to assess migraine type, severity, and the ...
Ameer Shaker
doaj   +1 more source

Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho   +6 more
doaj   +1 more source

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