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Systemic lupus erythematosus [PDF]

open access: yesNature Reviews Disease Primers, 2016
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Arvind Kaul   +2 more
exaly   +11 more sources

Systemic lupus erythematosus [PDF]

open access: yesBMJ, 2006
Systemic lupus erythematosus (SLE) is a multisystem autoimmune connective tissue disorder with various clinical presentations. It is prevalent among young women with a peak age of onset between the late teens and early 40s and a female to male ratio of 9:1. It is more common in certain ethnic groups, such as people with African or Asian ancestry.
Manson Jessica J, Rahman Anisur
  +10 more sources

Systemic lupus erythematosus [PDF]

open access: yesDrug and Therapeutics Bulletin, 1996
It has been estimated that about 3 in 10 000 people in Britain's cities have systemic lupus erythematosus (SLE)1 and the true figure may be higher.2 Forty years ago, approximately 50% of patients with SLE died within 4 years of diagnosis.3 Prospects have improved with refinements in therapy and the recognition of mild forms of the disease.
M S, Klein-Gitelman, M L, Miller
  +7 more sources

Cerebral Vein Thrombosis in the Antiphospholipid Syndrome: Analysis of a Series of 27 Patients and Review of the Literature

open access: yesBrain Sciences, 2021
(1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas   +9 more
doaj   +1 more source

Systemic Lupus Erythematosus [PDF]

open access: yesNew England Journal of Medicine, 2012
Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease, associated with autoantibody production and evidence for immune complex deposition among the many aspects of its pathophysiology. SLE occurs most commonly in women during their reproductive years.
Micha, Rapoport, Olga, Bloch
  +9 more sources

Systemic lupus erythematosus with trisomy X: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2022
Background The cause of systemic lupus erythematosus is not completely clear so far, but the prevalence of systemic lupus erythematosus is significantly increased in people with additional X chromosomes.
Fang Luo, Qiao Ye, Jie Shen
doaj   +1 more source

Peritonitis as the first presentation of systemic lupus erythematous: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Systemic lupus erythematosus is an inflammatory disease affecting several organs. Serositis is one of the systemic lupus erythematosus presentations, but peritonitis is a relatively rare presentation.
Zahedin Kheyri   +2 more
doaj   +1 more source

ASSESSMENT OF THE CARDIOVASCULAR RISK IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: CHOOSING THE APPROPRIATE TOOL

open access: yesArta Medica, 2020
Objectives. The aim of the research was to assess the cardiovascular risk in patients with systemic lupus erythematosus (SLE). Materials and Methods.
Victoria Sadovici-Bobeică   +5 more
doaj   +1 more source

Comparison of structural magnetic resonance imaging findings between neuropsychiatric systemic lupus erythematosus and systemic lupus erythematosus patients: A systematic review and meta-analysis [PDF]

open access: yes, 2017
Introduction: Neuropsychiatric systemic lupus erythematosus is often clinically challenging to diagnose, treat and monitor. Although brain magnetic resonance imaging is frequently performed before lumbar puncture in neuropsychiatric systemic lupus ...
Amin, O   +4 more
core   +1 more source

Diagnosis of tuberculosis with autoimmune hepatitis–systemic lupus erythematosus overlap syndrome: a case report

open access: yesJournal of Medical Case Reports, 2022
Background There is ample evidence indicating that immunosuppressive therapy or immune dysregulation in systemic lupus erythematosus increases the risk for tuberculosis.
Shekhar   +2 more
doaj   +1 more source

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