Results 281 to 290 of about 323,501 (341)

Impact of Lipid Profile Alterations on the Right Heart Function and Prognosis in Pre‐Capillary Pulmonary Hypertension Patients: A Prospective Cohort Study

open access: yesRespirology, EarlyView.
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo   +14 more
wiley   +1 more source

Effect of aspirin on maternal hemodynamics in Chinese women at high risk for preterm pre‐eclampsia: longitudinal study

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To compare the maternal hemodynamics of Chinese women at low and at high risk for preterm pre‐eclampsia (PE) and assess the differences in hemodynamic parameters between high‐risk women with or without prophylactic aspirin. Methods This was a prospective longitudinal case–control study of 857 Chinese women with a singleton pregnancy
X. Wang   +11 more
wiley   +1 more source

Role of aspirin therapy in modulating uterine artery resistance and placental growth between first and second trimesters of pregnancy

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate the impact of low‐dose aspirin (LDA) on placental size and uterine artery pulsatility index (UtA‐PI) by analyzing longitudinal changes between the first and second trimesters in pregnancies at high risk for early‐onset pre‐eclampsia (PE).
C. Trilla   +7 more
wiley   +1 more source

Microfluidic single‐cell technologies for immunotherapeutic target discovery: From design concepts to preclinical applications

open access: yesVIEW, EarlyView.
Immunotherapy leverages the immune system to treat cancer and autoimmune diseases but is hindered by cellular heterogeneity in tissues and immune landscapes. Single‐cell technologies, particularly microfluidic‐enabled omics, revolutionize disease understanding by resolving this complexity at unprecedented resolution.
Haopu Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Vasculitis associated with Ehrlichia canis and Babesia canis in a dog in the Netherlands

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract This report describes a case of severe, sudden‐onset, widespread vasculitis affecting a dog concurrently infected by Ehrlichia canis and Babesia canis. Following diagnostic investigations, the dog was suspected of an immune‐mediated vasculitis, possibly triggered by E. canis, B. canis or their combination. The lesions completely resolved after
Thomas Dijkxhoorn   +4 more
wiley   +1 more source

Catalytic IgG Antibodies Hydrolyze DNA, Histones, and HMGB1 in Systemic Lupus Erythematosus. [PDF]

open access: yesInt J Mol Sci
Melamud MM   +6 more
europepmc   +1 more source

Multiple Chronic Conditions Before Pregnancy and Risk of Adverse Maternal Health Outcomes: Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess the risks of perinatal emergency department (ED) use, hospitalisation and severe maternal morbidity or mortality (SMM‐M) associated with preconception MCC, according to the number of chronic conditions, complex MCC and co‐occurring cardiometabolic conditions. Design Population‐based cohort study.
Hilary K. Brown   +9 more
wiley   +1 more source

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