Results 201 to 210 of about 28,355 (295)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Righting Past Wrongs Through Restorative Justice: Managerial Motivations for Collaboration

open access: yesNonprofit Management and Leadership, EarlyView.
ABSTRACT Nonprofits are crucial to state collaborations as their embedded nature in communities allows them to gain the trust necessary to facilitate change and enhance strengths. As nonprofits collaborate with the public sector to tackle systemic challenges, understanding managerial motivations for collaboration and implications for social change is ...
Kara L. Lawrence   +2 more
wiley   +1 more source

Definitions Matter: BIPOC Nonprofits and Racial Disparities in Nonprofit Funding

open access: yesNonprofit Management and Leadership, EarlyView.
ABSTRACT BIPOC (Black, Indigenous, and People of Color) nonprofits have gained increased attention and funding; however, a lack of clear definition and identification persists. This ambiguity hinders our understanding of the BIPOC nonprofits population and racial disparities in nonprofit funding.
Shuyi Deng
wiley   +1 more source

Healthcare Professionals' Perspectives on Barriers to Reproductive Care Access in One Urban City: A Qualitative Study

open access: yesResearch in Nursing &Health, EarlyView.
ABSTRACT Inequities exist in reproductive care access for biological women of childbearing age from minoritized, racialized, and lower socioeconomic communities in the United States. While patient‐reported barriers are well documented, less is known about healthcare providers' perceptions of these challenges in urban, under‐resourced contexts ...
Roxanne Mirabal‐Beltran   +4 more
wiley   +1 more source

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang   +2 more
wiley   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

open access: yesThe Journal of Pathology, EarlyView.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi   +8 more
wiley   +1 more source

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