Results 41 to 50 of about 2,340,109 (293)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

FloodKAN: Integrating Kolmogorov–Arnold Networks for Efficient Flood Extent Extraction

Remote Sensing
Flood events are among the most destructive natural catastrophes worldwide and pose serious threats to socioeconomic systems, ecological environments, and the safety of human life and property. With the advancement of remote sensing technology, synthetic
Cong Wang, Xiaohan Zhang, Liwei Liu
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Incorporating compound temporal precipitation dynamics to enhance landslide susceptibility modeling

npj Natural Hazards
Precipitation plays a crucial role in landslides, which most studies have disregarded the impact of compound temporal precipitation. Here, we developed models that incorporate compound temporal precipitation, constructed by jointly characterizing long ...
Jingjing Wang, Jidong Wu, Hao Fang, Ming Wang   +3 more
doaj   +1 more source

Recognition of Building Structural Types Using Multisource Remote Sensing Data and Prior Knowledge

Remote Sensing
Accurate identification of building structural types (BSTs) is essential for seismic vulnerability assessment and disaster risk management. Traditional field survey methods are constrained by high costs, low efficiency, and limited scalability.
Lili Wang, Jidong Wu, Yachun He, Youtian Yang   +3 more
doaj   +1 more source

K-Correspondences, USCOs, and fixed point problems arising in discounted stochastic games

Fixed Point Theory and Applications, 2020
We establish a fixed point theorem for the composition of nonconvex, measurable selection valued correspondences with Banach space valued selections.
Frank H. Page, Jing Fu
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Rising worldwide challenges to climate-induced extreme low-production events of photovoltaic and wind power

Nature Communications
The global shift toward solar photovoltaic (PV) and wind power is crucial to climate mitigation, yet climate change may intensify extreme low-production (ELP) events and affect power reliability.
Qianzhi Wang, Kai Liu, Ming Wang, Zhao Zhang, Hao Chen, Lancui Liu, Jinshan Wu, Heran Zheng   +7 more
doaj   +1 more source

Quantitative assessment method of typhoon-induced photovoltaic damage and energy production losses: a case study of the 2024 Typhoon Yagi

Geomatics, Natural Hazards & Risk
Climate change has intensified the threat of typhoons to photovoltaic (PV) infrastructure. We present a quantitative assessment method to conduct typhoon-induced PV infrastructure loss assessment.
Anqi Li, Jidong Wu
doaj   +1 more source

Elimination of systemic risk in financial networks by means of a systemic risk transaction tax [PDF]

, 2016
Financial markets are exposed to systemic risk (SR), the risk that a major fraction of the system ceases to function, and collapses. It has recently become possible to quantify SR in terms of underlying financial networks where nodes represent financial ...
Poledna, Sebastian, Thurner, Stefan
core   +2 more sources