Results 111 to 120 of about 1,212,027 (321)
Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts
Advanced Science, Volume 12, Issue 29, August 7, 2025.Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian +10 more
wiley +1 more source
New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond
Annals of Neurology, Volume 98, Issue 2, Page 317-328, August 2025.The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr. +2 more
wiley +1 more source
Педиатрическая фармакология, 2019 Background. Currently, scleroderma is a rather rare disease, including among children. Despite the growing interest of investigators in this pathology, the problem of diagnosing oesophageal affection in various forms of systemic sclerosis remains under ...
Marina Ju. Stepanyan +3 more
doaj +1 more source
The role of nailfold capillaroscopy in interstitial lung diseases - Can it differentiate idiopathic cases from collagen tissue disease associated interstitial lung diseases? [PDF]
, 2015 Introduction: Nailfold capillaroscopy (NFC) is a non-invasive diagnostic test that is mostly used for early diagnosis of collagen tissue diseases (CTDs). We aimed to evaluate whether NFC findings could be a clue for discriminating idiopathic interstitial
Altınışık, Göksel +4 more
core +1 more source
Arthritis &Rheumatology, Volume 77, Issue 8, Page 1063-1076, August 2025.Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh +12 more
wiley +1 more source
A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma
Case Reports in Rheumatology, 2016 Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
Cody M. Lee +4 more
doaj +1 more source
Systemic sclerosis: current views of its pathogenesis. [PDF]
, 2003 Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
Monoclonal Gammopathies of Clinical Significance—Scleromyxedema: A Case Report and Literature Review
Clinical Case Reports, Volume 13, Issue 8, August 2025.ABSTRACT Scleromyxedema is an uncommon, chronic connective tissue disorder with an obscure etiology. It is distinguished by fibromyxoid skin lesions and elevated serum monoclonal immunoglobulin levels. The condition's rarity limits epidemiological data, making prevalence and incidence assessment difficult.
Shanshan Liang +4 more
wiley +1 more source
Revolutionizing Autoimmune Research: The Role of Caveolin‐1
Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao +8 more
wiley +1 more source
Some Immunologic Considerations in Focal Scleroderma and Progressive Systemic Sclerosis in Children [PDF]
, 1974 Virgil Hanson +4 more
openalex +1 more source