Results 121 to 130 of about 1,674,118 (394)

Adie’s Tonic Pupil in Systemic Sclerosis: A Rare Association

Case Reports in Ophthalmological Medicine, 2015
We report a rare association of Adie’s tonic pupil in a patient with systemic sclerosis who was otherwise systemically stable. This paper is an effort to unravel whether the tonic pupil and systemic sclerosis are an association by chance (which may be ...
Anusha Venkataraman, Bijnya Birajita Panda, Chandrasekhar Sirka   +2 more
doaj   +1 more source

Autologous Hematopoietic Stem Cell Therapy of the Subjects with Systemic Sclerosis: Electromyographic Results of the Masticatory Muscles

Prague Medical Report, 2020
Musculoskeletal system impairment is a major cause of functional alterations in subjects with systemic sclerosis. Autologous hematopoietic stem cell therapy (AHSCT) may have an important role in the treatment functional of systemic sclerosis patients ...
Thamyres Branco, Ligia Franco Oliveira, Marcelo Palinkas, Paulo Batista de Vasconcelos, Maria Carolina Oliveira, Belinda Pinto Simões, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo   +8 more
doaj   +1 more source

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H., FAGGIONI, Alberto, FARINA, Antonella, Farina, G. Alessandra, Lacconi, Valentina, Lenna, Stefania, MORRONE, Stefania, PERUZZI, Giovanna, QUARTA, SILVIA, ROSATO, Edoardo, Trojanowska, Maria, VESTRI, Anna Rita, York, Michael   +12 more
core   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Systemic sclerosis due to crystalline silica exposure among jewelry workers in Korea: two case reports

Annals of Occupational and Environmental Medicine, 2017
Background Occupational exposure to crystalline silica is a potential risk factor for various systemic autoimmune diseases including systemic sclerosis.
Jae Yoon Kim, Sang Yoon Do, Young Hoon Moon, Chul Gab Lee, Yun Sung Kim, Byung Soon Choi, Eun-A Kim, Han Soo Song   +7 more
doaj   +1 more source

CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis

Nature Communications, 2019
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis and vasculopathy. CXCL4 represents an early serum biomarker of severe SSc and likely contributes to inflammation via chemokine signaling pathways, but the exact role of ...
R. Lande, Ernest Y Lee, R. Palazzo, B. Marinari, I. Pietraforte, G. S. Santos, Yves Mattenberger, F. Spadaro, K. Stefanantoni, N. Iannace, A. Dufour, M. Falchi, Manuela Bianco, E. Botti, L. Bianchi, M. Alvarez, V. Riccieri, M. Truchetet, Gerard C L Wong, C. Chizzolini, L. Frasca   +20 more
semanticscholar   +1 more source

CXCR4 pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis [PDF]

, 2008
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
CAMPIONI, Diana, CUNEO, Antonio, Ferrari, L, FOTINIDI, Maria, LA CORTE, Renato, LANZA, Francesco, LO MONACO, Andrea, Moretti, S, TROTTA, Francesco   +8 more
core   +2 more sources

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Therapy of systemic sclerosis

Reumatismo, 2011
The treatment of the patient with systemic sclerosis has greatly improved in the last ten years, because of two kinds of achievements. A number of drugs have been demonstrated to be active in some disease manifestations like alveolitis, pulmonary hypertension and complicated Raynaud's phenomenon. Some of these drugs namely cyclophosphamide and iloprost
openaire   +5 more sources

Copeptin as a Biomarker of Microcirculation Alterations in Systemic Sclerosis

Clinical, Cosmetic and Investigational Dermatology, 2023
Magdalena Maciejewska,1 Albert Stec,2 Michał Zaremba,2 Cezary Maciejewski,3 Lidia Rudnicka,2 Mariusz Sikora4 1Department of Dermatology, Doctoral School of Medical University of Warsaw, Warsaw, Poland; 2Department of Dermatology, Medical ...
Maciejewska M, Stec A, Zaremba M, Maciejewski C, Rudnicka L, Sikora M   +5 more
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