Results 151 to 160 of about 1,628,316 (351)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Insights into the Relationship between Periodontitis and Systemic Sclerosis Based on the New Periodontitis Classification (2018): A Cross-Sectional Study

Diagnostics
(1) Background: This study aimed to assess the periodontitis burden in systemic sclerosis patients and the possible association between them, and the degree to which some potential risk factors and two potential diagnostic biomarkers may account for this
Andreea Ciurea, Alina Stanomir, Petra Șurlin, Iulia Cristina Micu, Cristina Pamfil, Daniel Corneliu Leucuța, Simona Rednic, Giulio Rasperini, Andrada Soancă, Adrian Bogdan Țigu, Alexandra Roman, Andrei Picoș, Ada Gabriela Delean   +12 more
doaj   +1 more source

Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study

Acta Dermato-Venereologica, 2017
Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort ...
Jeanette Halskou Hesselvig, Kristian Kofoed, Jashin J. Wu, Lene Dreyer, Gunnar Gislason, Ole Ahlehoff   +5 more
doaj   +1 more source

Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy

Przegląd Dermatologiczny, 2018
Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal, Marta Sar-Pomian, Joanna Czuwara, Lidia Rudnicka   +3 more
doaj   +1 more source

Gastrointestinal Manifestations of Systemic Sclerosis

Rheumatology, 2018
Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative alterations of the microvasculature leading to fibrosis and loss of function of the skin and internal organs.
Isabel M. McFarlane, Manjeet S. Bhamra, A. Kreps, S. Iqbal, Firas Al-Ani, Carla Saladini-Aponte, C. Grant, Soberjot Singh, Khalid Awwal, Kristaq Koci, Y. Saperstein, F. Arroyo-Mercado, Derek B. Laskar, Purna Atluri   +13 more
semanticscholar   +1 more source

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. [PDF]

, 1994
A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans,
Christiano, Angela M., Iozzo, Renato V., Jimenez, Sergio A., Rudnicka, Lidia, Uitto, Jouni, Varga, John   +5 more
core   +3 more sources

Current advances in the treatment of systemic sclerosis.

Current opinion in pharmacology (Print), 2022
H. Bukiri, E. Volkmann
semanticscholar   +1 more source

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

Science Translational Medicine, 2018
Platelet microparticles from patients with systemic sclerosis prompt endothelial cell activation, neutrophil recruitment, and lung fibrosis. Platelets nurture neutrophil damage Systemic sclerosis, or scleroderma, is a complicated inflammatory fibrotic ...
N. Maugeri, A. Capobianco, P. Rovere-Querini, G. Ramirez, E. Tombetti, P. Valle, A. Monno, V. D’Alberti, A. Gasparri, S. Franchini, A. D’Angelo, M. Bianchi, A. Manfredi   +12 more
semanticscholar   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

Annals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund, Connar Stanley James Westgate, Marie‐Louise Kulas Søborg, Agneta Henriette Snoer, Rigmor Højland Jensen, Thomas Folkman Hansen, Anja Sofie Petersen   +6 more
wiley   +1 more source