Results 151 to 160 of about 2,931,663 (352)

Systemic sclerosis in childhood [PDF]

Rheumatology, 2006
Juvenile systemic sclerosis (jSSc) is a rare disease of childhood, and the amount of published data is limited. It appears that its clinical presentation differs from adult disease and the limited form affects only very few children. The organ involvement pattern differs also from the adult form. Prognosis seems to be better with a 5-yr survival of 95%
openaire   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]

, 2013
Multiple sclerosis is an immune-mediated, demyelinating and neurodegenerative disease that currently lacks any neuroprotective treatments. Innovative neuroprotective trial designs are required to hasten the translational process of drug development.
Coffey, P, Baker, MD, Coffey Pete, Jackson, SJ, Gavin Giovannoni, Baker David, Samuel J. Jackson (468645), Zubair Ahmed (9352), Jackson Samuel J., Zubair Ahmed, Ahmed, Z, Mark D Baker, Pete Coffey (422262), David Baker, Samuel J Jackson, Gavin Giovannoni (125820), Giovannoni Gavin, Munro Peter, Ahmed Zubair, Pete Coffey, David Baker (11642), Peter Munro (479715), Peter Munro, Lidster Katie, Baker Mark D., Baker, D, Lidster, K, Mark D. Baker (146531), Katie Lidster, Munro, P, Katie Lidster (479714), Giovannoni, G   +31 more
core   +1 more source

Insights into the Relationship between Periodontitis and Systemic Sclerosis Based on the New Periodontitis Classification (2018): A Cross-Sectional Study

Diagnostics
(1) Background: This study aimed to assess the periodontitis burden in systemic sclerosis patients and the possible association between them, and the degree to which some potential risk factors and two potential diagnostic biomarkers may account for this
Andreea Ciurea, Alina Stanomir, Petra Șurlin, Iulia Cristina Micu, Cristina Pamfil, Daniel Corneliu Leucuța, Simona Rednic, Giulio Rasperini, Andrada Soancă, Adrian Bogdan Țigu, Alexandra Roman, Andrei Picoș, Ada Gabriela Delean   +12 more
doaj   +1 more source

Lower-limb Ulcers in Systemic Sclerosis: A Multicentre Retrospective Case-control Study

Acta Dermato-Venereologica, 2018
Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial ...
Gérôme Bohelay, Sophie Blaise, Pierre Levy, Antoine Claeys, Nathalie Baudot, Jean-Francois Cuny, Hervé Maillard, Florence Granel-Brocard, Thierry Boyé, Catherine Lok, Nathalie Bénéton, Camille Francès, Patricia Senet   +12 more
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Therapeutic Promise of Hyaluronidase in Systemic Sclerosis: A Systematic Review

Dermatology Practical & Conceptual
Introduction: Systemic sclerosis, also known as scleroderma, is a chronic disease marked by autoimmune-mediated damage to connective tissues leading to vascular damage, tissue injury, and fibrosis.
Anika Pulumati, Rachel Lin, Scott Elman
doaj   +1 more source

Vascular involvement in systemic sclerosis (scleroderma)

, 2011
Debendra Pattanaik1, Monica Brown2, Arnold E Postlethwaite11Division of Connective Tissue Diseases, Department of Medicine; 2Section of Pediatric Rheumatology Department of Pediatrics, University of Tennessee Health Science Center, and Department of ...
Brown M, Pattanaik D, Postlethwaite AE
core  

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy

Przegląd Dermatologiczny, 2018
Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal, Marta Sar-Pomian, Joanna Czuwara, Lidia Rudnicka   +3 more
doaj   +1 more source